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Disease Mice

Shanghai Model Organisms Center, Inc.

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • Pfkm-KO

    Pfkm-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pf
    • Exon : Exon 3
    • Disease : Glycogen Storag
    • KI/KO Gene : Pfkm
  • Ppm1k-KO

    Ppm1k-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pp
    • Exon : Exon 3
    • Disease : Maple Syrup Uri
    • KI/KO Gene : Ppm1k
  • Ppargc1a-KO

    Ppargc1a-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pp
    • Exon : Exon 3-5
    • Disease : Age Related Mac
    • KI/KO Gene : Ppargc1a
  • Pnpla3-I148M

    Pnpla3-I148M

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pn
    • Exon : Exon 3-5
    • Application : Non-Alcoholic F
    • Disease : Age Related Mac
  • Psen2-Flox

    Psen2-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ps
    • Exon : Exon s
    • Application : Non-Alcoholic F
    • Disease : Alzheimer's Dis
  • Prox1-Flox

    Prox1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pr
    • Exon : Exon 2
    • Application : Non-Alcoholic F
    • Disease : Dilated Cardiom
  • Prkci-Flox

    Prkci-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pr
    • Exon : Exon s
    • Application : Non-Alcoholic F
    • Disease : Type 2 Diabetes
  • Ptger4-Flox

    Ptger4-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pt
    • Exon : Exon 2
    • Application : Non-Alcoholic F
    • Disease : Dilated Cardiom
  • R26-CAG-LSL-hEGFR-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Dilated Cardiom
  • R26-CAG-LSL-hFGFR3*K562E-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Dilated Cardiom
  • R26-CAG-LSL-Kras*G12C-IRES-Luc

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Dilated Cardiom
  • R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Breast Cancer
  • R26-LSL-SmoM2W539L-IRES-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 2
    • Application : Medulloblastoma
    • Disease : Breast Cancer
  • Slc7a5-Flox

    Slc7a5-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 1
    • Application : Medulloblastoma
    • Disease : Autism Spectrum
  • Spr-KO

    Spr-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sp
    • Exon : Exon 2-3
    • Application : Medulloblastoma
    • Disease : Parkinson's Dis
  • Sox10-KO

    Sox10-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-So
    • Exon : Exon 4-5
    • Application : Research On Erk
    • Disease : Kallmann Syndro
  • Tbx20-KO

    Tbx20-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tb
    • Exon : Exon 2-6
    • Application : Research On Erk
    • Disease : Dilated Cardiom
  • Tbr1-KO

    Tbr1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tb
    • Exon : Exon 1-6
    • Application : Research On Erk
    • Disease : Autism Spectrum
  • Syn3-KO

    Syn3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sy
    • Exon : Exon 3
    • Application : Research On Erk
    • Disease : epilepsy
  • Syn2-KO

    Syn2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sy
    • Exon : Exon 2
    • Application : Research On Erk
    • Disease : Epilepsy
  • Srr-KO

    Srr-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sr
    • Exon : Exon 4
    • Application : Research On Erk
    • Disease : schizophrenia
  • Trp53-R172H/Kras-LSL-G12D

    Trp53-R172H/Kras-LSL-G12D

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Exon : Exon 4
    • Application : Research On Erk
    • Disease : schizophrenia
  • Trp53-Flox

    Trp53-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Medulloblastoma
  • Ywhaz-KO

    Ywhaz-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Yw
    • Exon : Exon 4
    • Application : Cancer Research
    • Disease : Schizophrenia
  • Wls-Flox

    Wls-Flox

    • Description : Model Descripti
    • Nomenclature : B6;129S-Wlstm1(
    • Exon : Exon 3
    • Application : Psoriasis-Like
    • Disease : Schizophrenia