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Slc7a5-Flox

SKU : BHAM00301

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-232095
Description	Model Description: These strains carry loxP sites flanking exon 1 of Slc7a5 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Slc7a5 gene. Official Symbol: Slc7a5 NCBI ID: 20539 MGI ID: 1298205 Ensembl ID: ENSMUSG00000040010 Pubmed: Slc7a5 Human Ortholog: SLC7A5
Nomenclature	C57BL/6JSmoc-Slc7a5^{em1(flox)Smoc}
Exon	Exon 1
Disease	Autism Spectrum Disorder
Disease	Nervous System Disease
KI/KO Gene	Slc7a5
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Tek-cre mice.
Synonyms	TA1, LAT1, 4F2LC, D0H16S474E

Reference	Tarlungeanu DC, Deliu E, Dotter CP, Kara M, Janiesch PC, Scalise M, Galluccio M, Tesulov M, Morelli E, Sonmez FM, Bilguvar K, Ohgaki R, Kanai Y, Johansen A, Esharif S, Ben-Omran T, Topcu M, Schlessinger A, Indiveri C, Duncan KE, Caglayan AO, Gunel M, Gleeson JG, Novarino G, Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder. Cell. 2016 Dec 01;167(6):1481-1494.e18

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