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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

1840 Result Found
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  • hTTR(2)

    hTTR(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tt
    • Strain : Repository Live
    • KI/KO Gene : Ttr
    • Synonyms : D17860, AA40876
  • hTSLP/hIL17RA

    hTSLP/hIL17RA

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ts
    • Strain : Embryo cryopres
    • Target : Cytokines
    • KI/KO Gene : TSLP
  • hVWF

    hVWF

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Vw
    • Strain : Developing
    • Target : Cytokines
    • KI/KO Gene : Vwf
  • R26-LSL-hIL15-Flag-IRES-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Strain : Repository Live
    • Target : Cytokines
    • KI/KO Gene : Gt(ROSA)26Sor
  • Rag2/IL2rg-KO/hVEGFR2

    Rag2/IL2rg-KO/hVEGFR2

    • Description : IL2rg-KO (NM-KO
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Repository Live
    • Target : Cytokines
    • KI/KO Gene : IL2RG
  • Rag2/IL2rg-KO(BALB/c)

    Rag2/IL2rg-KO(BALB/c)

    • Description : Exon 3 of Rag2
    • Nomenclature : BALB/cAnSmoc-Ra
    • Strain : Repository Live
    • Target : Cytokines
    • KI/KO Gene : IL2RG
  • Rag2-KO(Rag2-EGFP)

    Rag2-KO(Rag2-EGFP)

    • Description : A loxP-EGFP-Pol
    • Nomenclature : B6;129S-Rag2tm1
    • Strain : Embryo cryopres
    • Target : Cytokines
    • KI/KO Gene : Rag2
  • Tmem119-2A-tdTomato-2A-DTR

    • Description : 2A-tdTomato-2A-
    • Nomenclature : C57BL/6Smoc-Tme
    • Strain : Repository Live
    • Target : Cytokines
    • KI/KO Gene : Tmem119
  • Adh7-KO

    Adh7-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ad
    • Exon : Exon 3
    • Disease : Parkinson's Dis
    • Strain : Repository Live
  • Acadm-repeat(E8-10)

    Acadm-repeat(E8-10)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ac
    • Exon : Exon 10
    • Application : Medium Chain Ac
    • Disease : Medium Chain Ac
  • Apoa2-KO

    Apoa2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Homozygous Hype
  • Alpl-KO

    Alpl-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Exon : Exon 3-4
    • Application : Therapeutic Ant
    • Disease : Childhood Hypop
  • Aldob-KO

    Aldob-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Exon : Exon 3-6
    • Application : Hereditary Fruc
    • Disease : Hereditary Fruc
  • Bag3-Flox

    Bag3-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ba
    • Exon : Exon 4
    • Application : Hereditary Fruc
    • Disease : Dilated Cardiom
  • Axl-KO

    Axl-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ax
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • App-KO

    App-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Exon : Exon 3
    • Application : Neuronal Differ
    • Disease : Alzheimer's Dis
  • C4b-KO

    C4b-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-C4
    • Exon : Exon 3
    • Application : Inflammatory Re
    • Disease : Systemic Lupus
  • Brca1-Flox

    Brca1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Br
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Breast Cancer
  • Cdk4-KO

    Cdk4-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon 3-7
    • Application : The Protein Enc
    • Disease : Type 1 Diabetes
  • Cadps2-KO

    Cadps2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ca
    • Exon : Exon 5-6
    • Application : The Protein Enc
    • Disease : Autism Spectrum
  • Daam1-Flox

    Daam1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Da
    • Exon : Exon s
    • Application : The Protein Enc
    • Disease : Intrinsic Cardi
  • Ctf1-KO

    Ctf1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ct
    • Exon : Exon 2
    • Application : The Protein Enc
    • Disease : Type 2 Diabetes
  • Dmp1-KO

    Dmp1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dm
    • Exon : Exon 4-6
    • Application : Research On The
    • Disease : Autosomal Reces
  • En2-KO

    En2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dm
    • Exon : Exon 1
    • Application : Therapeutic Ant
    • Disease : Autism Spectrum
  • Egln3-Flox

    Egln3-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Eg
    • Exon : Exon 2-3
    • Application : Therapeutic Ant
    • Disease : cardiomyopathy
  • Fmo3-KO

    Fmo3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fm
    • Exon : Exon 3-6
    • Application : Therapeutic Ant
    • Disease : Fish-Odour Synd
  • F9-KO(2)

    F9-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-F9
    • Exon : Exon 1-8.
    • Application : Hemophilia B
    • Disease : hemophilia B
  • Gadd45gip1-Flox

    Gadd45gip1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon s
    • Application : Hemophilia B
    • Disease : Type 2 Diabetes
  • G6pc-KO

    G6pc-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-G6
    • Exon : Exon 3
    • Application : Hemophilia B
    • Disease : glycogen storag
  • Glul-Flox

    Glul-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gl
    • Exon : Exon 4-7
    • Application : Hemophilia B
    • Disease : Temporal Lobe E
  • Gla-KO

    Gla-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gl
    • Exon : Exon 2-3
    • Application : Fabry Disease R
    • Disease : Fabry Disease
  • Gucy2c-KO

    Gucy2c-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gu
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Obesity
  • Ins2-C96Y

    Ins2-C96Y

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-In
    • Exon : Exon 3
    • Application : Diabetes Relate
    • Disease : Diabetes
  • Il33-KO(3)

    Il33-KO(3)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Exon : Exon 2.
    • Application : Diabetes Relate
    • Disease : Alzheimer's dis
  • Il33-KO(2)

    Il33-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Exon : Exon 3-7.
    • Application : Immune
    • Disease : Alzheimer's dis
  • Il10-KO(BALB/c)

    Il10-KO(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Il
    • Exon : Exon 1-5
    • Application : Research On Erk
    • Disease : Inflammatory Bo
  • kif18A-KO

    kif18A-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-kif18At
    • Exon : Exon 2
    • Application : Male Infertilit
    • Disease : Inflammatory Bo
  • Jakmip1-KO

    Jakmip1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ja
    • Exon : Exon 4-8
    • Application : Male Infertilit
    • Disease : Autism Spectrum
  • Irs1-KO

    Irs1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ir
    • Exon : Exon 1
    • Application : Diabetes Relate
    • Disease : Type 2 Diabetes
  • Lrrc10-KO

    Lrrc10-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Exon : Exon 1
    • Application : Diabetes Relate
    • Disease : Dilated Cardiom
  • Mus81-KO

    Mus81-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mu
    • Exon : Exon 1-10
    • Application : Research On Hom
    • Disease : Marfan Syndrome
  • Mefv-hMEFV*V726A

    Mefv-hMEFV*V726A

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon 7-10
    • Application : Familial Medite
    • Disease : Familial Medite
  • Nos1-KO

    Nos1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-No
    • Exon : Exon 3
    • Application : Familial Medite
    • Disease : Hypertrophic Ca
  • Nf2-Flox

    Nf2-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nf
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Renal Cell Carc
  • Nexn-Flox

    Nexn-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ne
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Dilated Cardiom
  • Neil1-KO

    Neil1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ne
    • Exon : Exon 2-3
    • Application : Cancer Research
    • Disease : Abdominal Obesi
  • Ncoa6-Flox

    Ncoa6-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nc
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Dilated Cardiom
  • Park7-KO

    Park7-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pa
    • Exon : Exon 3-5
    • Application : A Sensor For Ox
    • Disease : Parkinson's Dis
  • Otc-KO

    Otc-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ot
    • Exon : Exon 2
    • Application : Research On Cdk
    • Disease : Ornithine Carba
  • Pianp-KO

    Pianp-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pi
    • Exon : Exon 3
    • Application : Research On Cdk
    • Disease : Autism Spectrum