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Home / Shanghai Model Organisms Center, Inc. / Animal Model / Humanized Knockins
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Humanized Knockins

Shanghai Model Organisms Center, Inc.

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Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

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  • hITGA11

    hITGA11

    hITGA11

    • Nomenclature : C57BL/6JSmoc-It
    • KI/KO Gene : Itga11
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : 4732459H24Rik
  • hKIT

    hKIT

    hKIT

    • Nomenclature : C57BL/6JSmoc-Ki
    • KI/KO Gene : Kit
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : W, Bs, Fdc, Ssm
  • hLILRB1-hLILRB4-Tg

    hLILRB1-hLILRB4-Tg

    hLILRB1-hLILRB4-Tg

    • Nomenclature : C57BL/6JSmoc-Tg
    • KI/KO Gene : LILRB4
    • Strain : Repository Live
    • Target : Cytokine Recept
    • Description : Model Descripti
  • hMS4A1(BALB/c)

    hMS4A1(BALB/c)

    hMS4A1(BALB/c)

    • Nomenclature : BALB/cAnSmoc-Ms
    • KI/KO Gene : Ms4a1
    • Strain : Repository Live
    • Description : Model Descripti
    • Synonyms : Cd20, Ly-44, Ms
  • hNOTCH1

    hNOTCH1

    hNOTCH1

    • Nomenclature : C57BL/6JSmoc-No
    • KI/KO Gene : Notch1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : N1, Mis6, Tan1,
  • hNCR1(2)

    hNCR1(2)

    hNCR1(2)

    • Nomenclature : C57BL/6JSmoc-Nc
    • KI/KO Gene : Ncr1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Ly94,NKp46
  • hPCSK9(2)

    hPCSK9(2)

    hPCSK9(2)

    • Nomenclature : C57BL/6JSmoc-Pc
    • KI/KO Gene : Pcsk9
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : FH3, PC9, Narc1
  • hOLR1

    hOLR1

    hOLR1

    • Nomenclature : C57BL/6JSmoc-Ol
    • KI/KO Gene : Olr1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : LOX-1, SR-EI, S
  • hPSCA

    hPSCA

    hPSCA

    • Nomenclature : C57BL/6JSmoc-Ps
    • KI/KO Gene : Psca
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : 2210408B04Rik
  • hROBO4

    hROBO4

    hROBO4

    • Nomenclature : C57BL/6JSmoc-Ro
    • KI/KO Gene : Robo4
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : AI593217, 12000
  • hHAO1(3)

    hHAO1(3)

    hHAO1(3)

    • Nomenclature : C57BL/6JSmoc-Ha
    • KI/KO Gene : Hao1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : GOX,Gox1,Hao-1
  • hHAO1(2)

    hHAO1(2)

    hHAO1(2)

    • Nomenclature : C57BL/6JSmoc-Ha
    • KI/KO Gene : Hao1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : GOX,Gox1,Hao-1
  • hICOS

    hICOS

    hICOS

    • Nomenclature : C57BL/6JSmoc-Ic
    • KI/KO Gene : Icos
    • Research Application : Immunotherapy
    • Strain : Embryo cryopres
    • Description : Model Descripti
  • hIFNAR1

    hIFNAR1

    hIFNAR1

    • Nomenclature : C57BL/6JSmoc-If
    • KI/KO Gene : Ifnar1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Ifar, Ifrc, Ifn
  • hIFNA1

    hIFNA1

    hIFNA1

    • Nomenclature : C57BL/6JSmoc-If
    • KI/KO Gene : Ifna1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Ifa1
  • hIGSF8

    hIGSF8

    hIGSF8

    • Nomenclature : C57BL/6JSmoc-Ig
    • KI/KO Gene : Igsf8
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : ESTM34,EWI-2,KC
  • hIGF1R(2)

    hIGF1R(2)

    hIGF1R(2)

    • Nomenclature : C57BL/6JSmoc-Ig
    • KI/KO Gene : Igf1r
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : hyft, CD221, IG
  • hIL12RB1

    hIL12RB1

    hIL12RB1

    • Nomenclature : C57BL/6JSmoc-Il
    • KI/KO Gene : Il12rb1
    • Strain : Repository Live
    • Description : Model Descripti
    • Synonyms : CD212, IL-12R(b
  • hIL13RA1

    hIL13RA1

    hIL13RA1

    • Nomenclature : C57BL/6JSmoc-Il
    • KI/KO Gene : Il13ra1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : NR4, Il13ra, CD
  • hIL2(M-NSG,2)

    hIL2(M-NSG,2)

    hIL2(M-NSG,2)

    • Nomenclature : M-NSG-Il2tm(hIL
    • KI/KO Gene : Il2
    • Strain : Repository Live
    • Description : Model Descripti
    • Synonyms : Il-2
  • hEPHA2

    hEPHA2

    hEPHA2

    • Nomenclature : C57BL/6JSmoc-Ep
    • KI/KO Gene : Epha2
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Eck, Myk2, Sek2
  • hENTPD1(BALB/c)

    hENTPD1(BALB/c)

    hENTPD1(BALB/c)

    • Nomenclature : BALB/cAnSmoc-En
    • KI/KO Gene : Entpd1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Cd39, AA408691,
  • hFOLR2

    hFOLR2

    hFOLR2

    • Nomenclature : C57BL/6JSmoc-Fo
    • KI/KO Gene : Folr2
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : FBP2, FR-P3, Fo
  • hGPR65

    hGPR65

    hGPR65

    • Nomenclature : C57BL/6JSmoc-Gp
    • KI/KO Gene : Gpr65
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Dig1, TDAG8, Gp
  • hCD16

    hCD16

    hCD16

    • Nomenclature : C57BL/6JSmoc-Fc
    • KI/KO Gene : Fcgr3
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • Description : Model Descripti
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