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Gucy2c-KO

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-200241
Description	Model Description: Exon 3 of Gucy2c gene was deleted to generate Gucy2c knockout mice. Official Symbol: Gucy2c NCBI ID: 14917 MGI ID: 106903 Ensembl ID: ENSMUSG00000042638 Pubmed: Gucy2c Human Ortholog: GUCY2C
Nomenclature	C57BL/6JSmoc-Gucy2c^em1Smoc
Exon	Exon 3
Application	Therapeutic Antibody Target
Disease	Obesity
Disease	Cardio-metabolic Disease
KI/KO Gene	Gucy2c
Synonyms	Gcc, GC-C, AI893437

Reference	Valentino MA, Lin JE, Snook AE, Li P, Kim GW, Marszalowicz G, Magee MS, Hyslop T, Schulz S, Waldman SA, A uroguanylin-GUCY2C endocrine axis regulates feeding in mice. J Clin Invest. 2011 Sep 1;121(9):3578-88

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