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Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

353 Result Found
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  • Grm5-KO

    Grm5-KO

    Grm5-KO

    • Nomenclature : C57BL/6JSmoc-Gr
    • Exon : Exon 4
    • KI/KO Gene : Grm5
    • Description : Model Descripti
    • Application : Endocrine, Cort
  • Gpr143-KO

    Gpr143-KO

    Gpr143-KO

    • Nomenclature : C57BL/6JSmoc-Gp
    • Exon : Exon 2
    • KI/KO Gene : Gpr143
    • Description : Model Descripti
    • Synonyms : Oa1
  • hTNFa-Tg(DBA)

    hTNFa-Tg(DBA)

    hTNFa-Tg(DBA)

    • Nomenclature : DBA-Tg(hTNFa)1S
    • KI/KO Gene : TNF
    • Description : Model Descripti
    • Application : Arthritis Mouse
    • Synonyms : DIF,TNFA,TNFSF2
  • Hmga1-KO

    Hmga1-KO

    Hmga1-KO

    • Nomenclature : C57BL/6JSmoc-Hm
    • Exon : Exon 3-5
    • KI/KO Gene : Hmga1
    • Description : Model Descripti
    • Synonyms : Hmgi, Hmgy, Hmg
  • Hivep2-KO

    Hivep2-KO

    Hivep2-KO

    • Exon : Exon 5
    • KI/KO Gene : Hivep2
    • Description : Model Descripti
    • Synonyms : MIBP1, Shn-2, M
    • Disease : Schizophrenia
  • Lat-Y136F

    Lat-Y136F

    Lat-Y136F

    • Nomenclature : C57BL/6JSmoc-La
    • KI/KO Gene : Lat
    • Description : Model Descripti
    • Application : Igg4-Related Di
    • Synonyms : pp36, p36-38
  • Kras-LSL-G12D

    Kras-LSL-G12D

    Kras-LSL-G12D

    • Nomenclature : C57BL/6JSmoc-Kr
    • Exon : Exon 2
    • KI/KO Gene : Kras
    • Description : Model Descripti
    • Application : Cancer Research
  • KPC(2)

    KPC(2)

    KPC(2)

    • Nomenclature : C57BL/6JSmoc-Tr
    • KI/KO Gene : Trp53
    • Description : Model Descripti
    • Application : Spontaneous Pan
    • Synonyms : bbl; bfy; bhy;
  • Lmx1b-Flox

    Lmx1b-Flox

    Lmx1b-Flox

    • Nomenclature : C57BL/6JSmoc-Lm
    • Exon : Exon 4-6
    • KI/KO Gene : Lmx1b
    • Description : Model Descripti
    • Application : Research On Dop
  • Lep-KO

    Lep-KO

    Lep-KO

    • Nomenclature : B6;129S-Leptm1S
    • Exon : Exon 2
    • KI/KO Gene : Lep
    • Description : Model Descripti
    • Application : Insulin Resista
  • Ldlr-KO(2)

    Ldlr-KO(2)

    Ldlr-KO(2)

    • Nomenclature : C57BL/6JSmoc-Ld
    • Exon : Exon 4.
    • KI/KO Gene : Ldlr
    • Description : Model Descripti
    • Synonyms : Hlb301
  • Mecp2-Flox

    Mecp2-Flox

    Mecp2-Flox

    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon 2-3.
    • KI/KO Gene : Mecp2
    • Description : Model Descripti
    • Application : Rett Syndrome,
  • Mdm4-Flox

    Mdm4-Flox

    Mdm4-Flox

    • Nomenclature : C57BL/6JSmoc-Md
    • Exon : Exon s
    • KI/KO Gene : Mdm4
    • Description : Model Descripti
    • Synonyms : Mdmx, C85810, A
  • Myocd-Flox

    Myocd-Flox

    Myocd-Flox

    • Nomenclature : C57BL/6JSmoc-My
    • Exon : Exon s
    • KI/KO Gene : Myocd
    • Description : Model Descripti
    • Synonyms : Srfcp, BSAC2A
  • Mertk-KO

    Mertk-KO

    Mertk-KO

    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon 2
    • KI/KO Gene : Mertk
    • Description : Model Descripti
    • Application : Therapeutic Ant
  • Nipbl-Flox

    Nipbl-Flox

    Nipbl-Flox

    • Nomenclature : B6;129S-Nipbltm
    • Exon : Exon 5
    • KI/KO Gene : Nipbl
    • Description : Model Descripti
    • Application : Cornelia De Lan
  • Nexn-KO

    Nexn-KO

    Nexn-KO

    • Exon : Exon 5-13
    • KI/KO Gene : Nexn
    • Description : Model Descripti
    • Synonyms : NELIN, AA553326
    • Disease : dilated cardiom
  • Nexmif-KO

    Nexmif-KO

    Nexmif-KO

    • Nomenclature : C57BL/6JSmoc-Ne
    • Exon : Exon 4
    • KI/KO Gene : Nexmif
    • Description : Model Descripti
    • Synonyms : Xpn, C77370, C7
  • Nrcam-KO

    Nrcam-KO

    Nrcam-KO

    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 5
    • KI/KO Gene : Nrcam
    • Description : Model Descripti
    • Synonyms : Bravo, mKIAA034
  • Nphs2-R231Q

    Nphs2-R231Q

    Nphs2-R231Q

    • Nomenclature : C57BL/6JSmoc-Np
    • KI/KO Gene : Nphs2
    • Description : Model Descripti
    • Synonyms : PDCN, SRN1
    • Disease : Hereditary Glom
  • Pah-KO

    Pah-KO

    Pah-KO

    • Nomenclature : C57BL/6JSmoc-Pa
    • Exon : Exon 2-5
    • KI/KO Gene : Pah
    • Description : Model Descripti
    • Synonyms : AW106920
  • Opg-KO

    Opg-KO

    Opg-KO

    • Nomenclature : B6.129S-Tnfrsf1
    • Exon : Exon 2
    • KI/KO Gene : Tnfrsf11b
    • Description : Model Descripti
    • Application : Osteoporosis
  • Nrxn1-KO

    Nrxn1-KO

    Nrxn1-KO

    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 6
    • KI/KO Gene : Nrxn1
    • Description : Model Descripti
    • Synonyms : mKIAA0578, 1700
  • Nrp2-KO

    Nrp2-KO

    Nrp2-KO

    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 2
    • KI/KO Gene : Nrp2
    • Description : Model Descripti
    • Synonyms : Np2, Np-2, Npn2
  • Pink1-KO

    Pink1-KO

    Pink1-KO

    • Nomenclature : C57BL/6JSmoc-Pi
    • Exon : Exon 2-4
    • KI/KO Gene : Pink1
    • Description : Model Descripti
    • Application : Mitochondrial H
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