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Lmx1b-Flox

SKU : BHAM00164

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-200117
Description	Model Description: These mice carry loxP sites flanking exon 4-6 of Lmx1b gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lmx1b gene. Official Symbol: Lmx1b NCBI ID: 16917 MGI ID: 1100513 Ensembl ID: ENSMUSG00000038765 Pubmed: Lmx1b Human Ortholog: LMX1B
Nomenclature	C57BL/6JSmoc-Lmx1b^{em1(flox)Smoc}
Exon	Exon 4-6
Application	Research On Dopaminergic Neurogenesis And Sudden Infant Death Syndrome (Sids) Susceptibility Pathway
Disease	Nail-Patella Syndrome
Disease	Nervous System Disease
KI/KO Gene	Lmx1b
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with NPHS2-cre mice.
Synonyms	Icst, LMX1.1, LMX1.2

Reference	MGI:5904009 Suleiman H, Heudobler D, Raschta AS, Zhao Y, Zhao Q, Hertting I, Vitzthum H, Moeller MJ, Holzman LB, Rachel R, Johnson R, Westphal H, Rascle A, Witzgall R, The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes. Dev Biol. 2007 Apr 15;304(2):701-12

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