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Mecp2-Flox

SKU : BHAM00171

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-190001
Description	Model Description: These mice carry loxP sites flanking exon 2-3. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene. Official Symbol: Mecp2 NCBI ID: 17257 MGI ID: 99918 Ensembl ID: ENSMUSG00000031393 Pubmed: Mecp2 Human Ortholog: MECP2
Nomenclature	C57BL/6JSmoc-Mecp2^{tm2(flox)Smoc}
Exon	Exon 2-3.
Application	Rett Syndrome, Autism
Disease	Rett Syndrome
Disease	Nervous System Disease
KI/KO Gene	Mecp2
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Nes-cre mice.
Synonyms	Mbd5, WBP10, 1500041B07Rik, D630021H01Rik

Reference	MGI:3691620 Chen RZ, Akbarian S, Tudor M, Jaenisch R, Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet. 2001 Mar;27(3):327-31

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