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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

1840 Result Found
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  • Alb-DreERT2

    Alb-DreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Strain : Repository Live
    • KI/KO Gene : Alb
    • Synonyms : Alb1, Alb-1,
  • Atp4b-IRES-CreERT2(2)

    Atp4b-IRES-CreERT2(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-At
    • Strain : Embryo cryopres
    • KI/KO Gene : Atp4b
    • Synonyms : AV080843
  • Akt1-KO

    Akt1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ak
    • Exon : Exon 2
    • Application : Pro-Inflammator
    • Disease : Schizophrenia
  • Angptl6-KO

    Angptl6-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-An
    • Exon : Exon 3
    • Application : Pro-Inflammator
    • Disease : Obesity
  • Avpr1a-KO

    Avpr1a-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Av
    • Exon : Exon 1-2
    • Application : Therapeutic Ant
    • Disease : Schizophrenia
  • Arx-Flox

    Arx-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ar
    • Exon : Exon s
    • Application : Therapeutic Ant
    • Disease : Early Infantile
  • Arg1-KO

    Arg1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ar
    • Exon : Exon 3
    • Application : Innate Immune S
    • Disease : Hyperargininemi
  • Ar-Flox

    Ar-Flox

    • Description : Model Descripti
    • Nomenclature : B6;129S-Artm1(f
    • Exon : Exon 2
    • Application : Innate Immune S
    • Disease : Prostate Cancer
  • Btd-KO

    Btd-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Bt
    • Exon : Exon 2-3
    • Application : Metabolism And
    • Disease : Biotinidase Def
  • Bmp1-Flox

    Bmp1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Bm
    • Exon : Exon 3-6
    • Application : Research On Lip
    • Disease : Osteogenesis Im
  • Cdkal1-Flox

    Cdkal1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon s
    • Application : Research On Lip
    • Disease : Type 2 Diabetes
  • CAG-hACE2-IRES-Luc-Tg

    CAG-hACE2-IRES-Luc-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Exon : Exon s
    • Application : Corona Virus Re
    • Disease : Type 2 Diabetes
  • Cox7a1-KO

    Cox7a1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Co
    • Exon : Exon 2-3
    • Application : Corona Virus Re
    • Disease : Dilated Cardiom
  • Chrnb2-KO

    Chrnb2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ch
    • Exon : Exon 2
    • Application : Corona Virus Re
    • Disease : Autism Spectrum
  • Chd8-KO

    Chd8-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ch
    • Exon : Exon 2-3
    • Application : Corona Virus Re
    • Disease : Autism Spectrum
  • Dag1-Flox

    Dag1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Da
    • Exon : Exon 4
    • Application : Corona Virus Re
    • Disease : Dilated Cardiom
  • Ctsc-KO

    Ctsc-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ct
    • Exon : Exon 2-3
    • Application : Papillon-Lefevr
    • Disease : Schizophrenia
  • Dlgap4-KO

    Dlgap4-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dl
    • Exon : Exon 4
    • Application : Papillon-Lefevr
    • Disease : Autism Spectrum
  • Disc1-KO

    Disc1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Di
    • Exon : Exon 2
    • Application : Papillon-Lefevr
    • Disease : Schizophrenia
  • Esrrb-Flox

    Esrrb-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Es
    • Exon : Exon s
    • Application : Papillon-Lefevr
    • Disease : Dilated Cardiom
  • Fas-KO(BALB/c)

    Fas-KO(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Fa
    • Exon : Exon 2
    • Application : Immune-Related
    • Disease : Systemic Lupus
  • Fah-KO

    Fah-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fa
    • Exon : Exon 8
    • Application : Tyrosinemia Typ
    • Disease : Tyrosinemia Typ
  • Gad2-KO

    Gad2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon 3-5
    • Application : Therapeutic Ant
    • Disease : Epilepsy
  • Gabra1-KO

    Gabra1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon 4
    • Application : Epilepsy Resear
    • Disease : Epilepsy
  • Fmr1-KO

    Fmr1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fm
    • Exon : Exon 2
    • Application : Epilepsy Resear
    • Disease : Autism Spectrum
  • Gpr132-KO

    Gpr132-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gp
    • Exon : Exon 3
    • Application : Epilepsy Resear
    • Disease : Autoimmune Dise
  • Gpr12-KO

    Gpr12-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gp
    • Exon : Exon 2
    • Application : Epilepsy Resear
    • Disease : Obesity
  • H11-CAG-LSL-Mycn-IRES-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ig
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Neuroblastoma
  • Grhpr-KO

    Grhpr-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gr
    • Exon : Exon 2-6
    • Application : Cancer Research
    • Disease : Primary Hyperox
  • Ids-KO

    Ids-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Id
    • Exon : Exon 2
    • Application : Diseases Associ
    • Disease : Mucopolysacchar
  • Ikbkg-Flox

    Ikbkg-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ik
    • Exon : Exon 4
    • Application : Diseases Associ
    • Disease : Fatty Liver Dis
  • Ldb3-Flox

    Ldb3-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ld
    • Exon : Exon s
    • Application : Diseases Associ
    • Disease : Dilated Cardiom
  • Kdm3A-KO

    Kdm3A-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Kd
    • Exon : Exon 5
    • Application : Diseases Associ
    • Disease : Obesity
  • Lgals3-KO

    Lgals3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lg
    • Exon : Exon 3-4
    • Application : Immune-Related
    • Disease : Obesity
  • Mapk1-Flox

    Mapk1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Exon : Exon 2-3
    • Application : Immune-Related
    • Disease : Autism Spectrum
  • Mme-KO

    Mme-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mm
    • Exon : Exon 4-7
    • Application : Therapeutic Ant
    • Disease : Alzheimer's Dis
  • Mkks-KO

    Mkks-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mk
    • Exon : Exon 4
    • Application : Therapeutic Ant
    • Disease : Obesity
  • Minar2-KO

    Minar2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mi
    • Exon : Exon 2-3
    • Application : Therapeutic Ant
    • Disease : Parkinson's Dis
  • Met-Flox

    Met-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon 16
    • Application : Therapeutic Ant
    • Disease : Gilles De La To
  • Nefl-N98S

    Nefl-N98S

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ne
    • Exon : Exon 16
    • Application : Peroneal Muscul
    • Disease : Charcot-Marie-T
  • Nppa-KO

    Nppa-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Np
    • Exon : Exon 1
    • Application : Peroneal Muscul
    • Disease : Hypertension
  • Npc1-Flox

    Npc1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Np
    • Exon : Exon 9
    • Application : Lipoprotein Met
    • Disease : Niemann-Pick Di
  • Notch3-R170C

    Notch3-R170C

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-No
    • Exon : Exon 9
    • Application : Hereditary Mult
    • Disease : CADASIL 1
  • Oprm1-KO

    Oprm1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Op
    • Exon : Exon 3
    • Application : Dopamine System
    • Disease : Autism Spectrum
  • Plp1-Flox

    Plp1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pl
    • Exon : Exon 3
    • Application : The Study Of Gl
    • Disease : Hereditary Spas
  • Plau-KO

    Plau-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pl
    • Exon : Exon 3-4
    • Application : Alzheimer'S Dis
    • Disease : Alzheimer's Dis
  • Pin1-KO

    Pin1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pl
    • Exon : Exon 2-4
    • Application : Alzheimer'S Dis
    • Disease : Alzheimer's Dis
  • Pfkm-KO

    Pfkm-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pf
    • Exon : Exon 3
    • Application : Alzheimer'S Dis
    • Disease : Glycogen Storag
  • Ppm1k-KO

    Ppm1k-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pp
    • Exon : Exon 3
    • Application : Alzheimer'S Dis
    • Disease : Maple Syrup Uri
  • Ppargc1a-KO

    Ppargc1a-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pp
    • Exon : Exon 3-5
    • Application : Alzheimer'S Dis
    • Disease : Age Related Mac