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Ar-Flox

SKU : BHAM00029

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-00110
Description	Model Description: These mice carry loxP sites flanking exon 2 of Ar gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ar gene. Official Symbol: Ar NCBI ID: 11835 MGI ID: 88064 Ensembl ID: ENSMUSG00000046532 Pubmed: Ar Human Ortholog: AR
Nomenclature	B6;129S-Ar^{tm1(flox)Smoc}
Exon	Exon 2
Disease	Prostate Cancer
Disease	Cardio-metabolic Disease
KI/KO Gene	Ar
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Pten-Flox(NM-CKO-18004) and Pbsn-cre mice.
Synonyms	Tfm AW320017?AIS8 DHTR HUMARA HYSP1 KD NR3C4 SBMA SMAX1

Reference	MGI:2668857 Mulholland DJ, Tran LM, Li Y, Cai H, Morim A, Wang S, Plaisier S, Garraway IP, Huang J, Graeber TG, Wu H, Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth. Cancer Cell. 2011 Jun 14;19(6):792-804

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