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Ikbkg-Flox

SKU : BHAM00147

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-2100819
Description	Model Description: These mice carry loxP sites flanking exon 4 of Ikbkg gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ikbkg gene. Official Symbol: Ikbkg NCBI ID: 16151 MGI ID: 1338074 Ensembl ID: ENSMUSG00000004221 Pubmed: Ikbkg Human Ortholog: IKBKG
Nomenclature	C57BL/6JSmoc-Ikbkg^{em1(flox)Smoc}
Exon	Exon 4
Disease	Fatty Liver Disease
Disease	Cardio-metabolic Disease
KI/KO Gene	Ikbkg
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Alb1-cre mice.
Synonyms	NEMO, IKK(g), AI848108, AI851264, AW124339, 1110037D23Rik

Reference	MGI:2653187 Luedde T, Beraza N, Kotsikoris V, van Loo G, Nenci A, De Vos R, Roskams T, Trautwein C, Pasparakis M, Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell. 2007 Feb;11(2):119-32

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