Tissue / cell preparation (Human cytochrome B enriched cells).
Purification
Affinity Chromatography
Isotype
IgG
Tested Application
FCM
Uniprotkb
P08962 (UniProt, ExPASy)
Gene Id
967
Availability
Shipped within 2-3 weeks.
Target
Tetraspanin 30 / TSPAN30 (CD63)
Storage
Aliquot and store in the dark at 2°C to 8°C. Avoid exposure to light.
Reactivity
Human
Molecular Weight
53 kDa
Note
This product is for research use only.
Clonality
monoclonal
Buffer
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide
Recommended Dilution
FCM: 20 µl/1 million cells. Optimal dilutions/concentrations should be determined by the end user.
Description
CD63 is a 53 kDa, type III lysosomal glycoprotein, expressed on activated platelets, monocytes and macrophages. CD63 contains four hydrophobic transmembrane domains with a major extracellular region of 95 amino acids between transmembrane segments 3 and 4. The COOH-terminal sequence SGYEVM functions as a lysosomal targeting sequence. This molecule is also referred highly to as LIMP, gp55,melanoma-associated antigen ME491, Pltgp40, LAMP-3 and is a member of the tetraspan transmembrane 4 superfamily (TM4SF). It is also widely expressed on surface and in the cytoplasm of various hematopoietic (monocytes, macrophages) and non-hematopoietic cells (endothelium, fibroblasts, osteoclasts, smooth muscle). Its cellular function has not been fully elucidated. Reports suggest this as a useful molecule to study platelet activation.
Tetraspanin 30 / TSPAN30 (CD63) Antibody (PerCP)
Reviews of Tetraspanin 30 / TSPAN30 (CD63) Antibody (PerCP)