Aliquot and store in the dark at 2°C to 8°C. Avoid exposure to light.
Reactivity
Human
Molecular Weight
150 kDa
uniprot enrty name
ITA3_HUMAN
Note
This product is for research use only.
Clonality
monoclonal
Buffer
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide
Recommended Dilution
FCM: 20 µl/1 million cells. Optimal dilutions/concentrations should be determined by the end user.
Description
Reacts with α 3 integrin, a 150 kDa transmembrane glycoprotein which non-covalently associates with integrin b 1 (CD 29) to form the α 3b1 (CD49c/CD29,VLA-3) complex. CD49c is expressed mostly on endothelial and epithelial cells (basal epidermal layers). It is not expressed on platelets and is expressed weakly on peripheral blood leukocytes. The CD49c/CD29 complex serves as an adhesive receptor for kalinin or epiligrin. This interaction may be important for thymocyte interaction with thymic epithelium. This antibody is suitable for immunohistochemical staining on acetone-fixed frozen tissue sections.1-3
Integrin Alpha 3 (ITGA3) Antibody (PerCP)
Reviews of Integrin Alpha 3 (ITGA3) Antibody (PerCP)