Aliquot and store in the dark at 2°C to 8°C. Avoid exposure to light.
Reactivity
Human, Monkey
Molecular Weight
25 kDa
uniprot enrty name
ITA2B_HUMAN
Note
This product is for research use only.
Clonality
monoclonal
Buffer
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide
Recommended Dilution
FCM: 20 µl/1 million cells. Optimal dilutions/concentrations should be determined by the end user.
Description
The monoclonal antibody recognizes the intact platelet gpIIb/IIIa complex, i.e. it does not bind to dissociated gpIIb or gpIIIa. The antibody does not bind to platelets from patients with Glanzmann Thrombasthenia and does not recognize the vitronectin receptor, which contains gpIIa as a beta subunit (cf. CD61). The monoclonal antibody activates human thrombocytes and induces thrombocyte aggregation in the absence of thrombocyte inhibitors such as EDTA.
Integrin Alpha 2B (ITGA2B) Antibody (PerCP)
Reviews of Integrin Alpha 2B (ITGA2B) Antibody (PerCP)