Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Reactivity
Human, Mouse, Rat
uniprot enrty name
SRC8_HUMAN
Note
This product is for research use only.
Clonality
polyclonal
Buffer
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Description
Phospho-Cortactin (Tyr421) Antibody detects endogenous levels of Cortactin only when phosphorylated at Tyrosine 421. cortactin a cytoskeletal protein that that is involved in coordinating actin reorganization during cell movement. Localizes at the leading edge of lamellipodia during cell migration. Its amino-terminal acidic domain associates with the Arp2/3 and WASP complex at F-actin branches.