JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.
Loding Loading ....
Filter
Sort By

Humanized Knockins

Shanghai Model Organisms Center, Inc.

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

  • hIL18BP

    hIL18BP

    • Strain : Repository Live
    • KI/KO Gene : Il18bp
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL21/hIL21R

    hIL21/hIL21R

    • Strain : Repository Live
    • KI/KO Gene : IL21
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il2
    • Description : hIL21(NM-HU-200
  • hIL2/hIL2RA/hIL2RB/hIL2RG

    hIL2/hIL2RA/hIL2RB/hIL2RG

    • Strain : Repository Live
    • KI/KO Gene : IL2
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il2
    • Description : hIL2/hIL2RA(NM-
  • hIL2/hIL2RA(BALB/c)

    hIL2/hIL2RA(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : IL2
    • Research Application : Humanized Drug
    • Nomenclature : BALB/cAnSmoc-Il
    • Description : The endogenous
  • hIL5/hIL5R(2)

    hIL5/hIL5R(2)

    • Strain : Repository Live
    • KI/KO Gene : IL5
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il5
    • Description : The endogenous
  • hIL4-Tg(NMG)(2)

    hIL4-Tg(NMG)(2)

    • Strain : Developing
    • KI/KO Gene : Gt(ROSA)26Sor
    • Research Application : Humanized Drug
    • Nomenclature : NOD-PrkdcscidIl
    • Description : These transgeni
  • hITGB1

    hITGB1

    • Strain : Repository Live
    • KI/KO Gene : Itgb1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Itg
    • Description : The endogenous
  • hIL9

    hIL9

    • Strain : Repository Live
    • KI/KO Gene : Il9
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il9
    • Description : The endogenous
  • hLILRA4

    hLILRA4

    • Strain : Sperm cryoprese
    • KI/KO Gene : Lair1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Lai
    • Description : The endogenous
  • hLGALS9

    hLGALS9

    • Strain : Repository Live
    • KI/KO Gene : Lgals9
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Lga
    • Description : The endogenous
  • hMELTF

    hMELTF

    • Strain : Embryo cryopres
    • KI/KO Gene : Klrg1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Mel
    • Description : The endogenous
  • hMASP2

    hMASP2

    • Strain : Repository Live
    • KI/KO Gene : Masp2
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Mas
    • Description : The endogenous
  • hNECTIN4

    hNECTIN4

    • Strain : Repository Live
    • KI/KO Gene : Nectin4
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Nec
    • Description : The endogenous
  • hOX40L(2)

    hOX40L(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : Tnfsf4
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : The endogenous
  • hOCLN

    hOCLN

    • Strain : Embryo cryopres
    • KI/KO Gene : Ocln
    • Research Application : Hcv Infection R
    • Nomenclature : C57BL/6Smoc-Ocl
    • Description : The endogenous
  • hNRP1

    hNRP1

    • Strain : Embryo cryopres
    • KI/KO Gene : Nrp1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Nrp
    • Description : The endogenous
  • CAG-hACE2-IRES-Luc-Tg

    CAG-hACE2-IRES-Luc-Tg

    • Strain : Repository Live
    • Research Application : Corona Virus R
    • Nomenclature : C57BL/6Smoc-Tgt
    • Description : The transgene i
    • Synonyms : ACEH
  • h4-1BB(2)/hOX40

    h4-1BB(2)/hOX40

    • Strain : Embryo cryopres
    • KI/KO Gene : 4-1BB
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : hTNFRSF9(NM-HU-
  • hAppNL-F

    hAppNL-F

    • Strain : Embryo cryopres
    • KI/KO Gene : App
    • Research Application : Alzheimer'S Dis
    • Nomenclature : C57BL/6Smoc-App
    • Description : The endogenous
  • hAGT

    hAGT

    • Strain : Repository Live
    • KI/KO Gene : Agt
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Agt
    • Description : The endogenous
  • hB7H3/hPD-1

    hB7H3/hPD-1

    • Strain : Embryo cryopres
    • KI/KO Gene : CD276
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cd2
    • Description : hB7-H3(NM-HU-00
  • hB7H3/hCD28

    hB7H3/hCD28

    • Strain : Embryo cryopres
    • KI/KO Gene : CD276
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cd2
    • Description : hB7-H3(NM-HU-00
  • hB2M-HLA A2.1(NMG)

    hB2M-HLA A2.1(NMG)

    • Strain : Developing
    • KI/KO Gene : H2-D1
    • Research Application : Humanized Drug
    • Nomenclature : NOD-PrkdcscidIl
    • Description : The endogenous
  • hC1S

    hC1S

    • Strain : Repository Live
    • KI/KO Gene : C1s1
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-C1s
    • Description : The endogenous
  • hCCR4(2)

    hCCR4(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : Il12rb1
    • Nomenclature : C57BL/6Smoc-Ccr
    • Research Application : Humanized Drug
    • Description : The endogenous