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Humanized Knockins
Shanghai Model Organisms Center, Inc.
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hCD81/hOCLN
- Strain : Embryo cryopres
- KI/KO Gene : CD81
- Research Application : Hcv Infection R
- Nomenclature : C57BL/6Smoc-Cd8
- Description : These mice are
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hCSF1(NMG)
- Strain : Developing
- KI/KO Gene : Csf1
- Research Application : Humanized Drug
- Nomenclature : NOD-PrkdcscidIl
- Description : The endogenous
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hCTLA-4/Cd8a-IRES-Luc-2A-EGFP
- Strain : Embryo cryopres
- KI/KO Gene : Cd8a
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Ctl
- Description : hCTLA4(NM-HU-00
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Rag2-KO/hVEGFR2
- Strain : Embryo cryopres
- KI/KO Gene : Rag2
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Kdr
- Description : The Rag2 gene o
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hIL5/hIL5R
- Nomenclature : C57BL/6JSmoc-Il
- KI/KO Gene : IL5
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Description : Model Descripti
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hIL7(M-NSG)
- Nomenclature : M-NSG-Il7tm(hIL
- KI/KO Gene : Il7
- Strain : Repository Live
- Description : Model Descripti
- Synonyms : Il-7, hlb368, A
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hKDR(BALB/c)
- Nomenclature : BALB/cAnSmoc-Kd
- KI/KO Gene : Kdr
- Strain : Developing
- Description : Model Descripti
- Synonyms : orv, Flk1, Ly73
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hMUC1-c.462insC
- Nomenclature : C57BL/6JSmoc-Mu
- KI/KO Gene : Muc1
- Strain : Repository Live
- Description : Model Descripti
- Synonyms : EMA, CD227, Muc
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hSIGLEC15(BALB/c)
- Nomenclature : BALB/cAnSmoc-Si
- KI/KO Gene : Siglec15
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Target : Immune Checkpoi
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