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Humanized Knockins
Shanghai Model Organisms Center, Inc.
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hCD22(BALB/c)
- Nomenclature : BALB/cAnSmoc-Cd
- KI/KO Gene : Cd22
- Strain : Developing
- Description : Model Descripti
- Synonyms : Lyb8, Lyb-8, A5
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hCD3EDG/hB7H3
- Nomenclature : C57BL/6JSmoc-Cd
- KI/KO Gene : CD276
- Strain : Developing
- Target : Immune Checkpoi
- Description : Model Descripti
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hCD47(BALB/c)
- Nomenclature : BALB/cAnSmoc-Cd
- KI/KO Gene : Cd47
- Research Application : Immunotherapy
- Strain : Developing
- Description : Model Descripti
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hCEACAM1(2)
- Nomenclature : C57BL/6JSmoc-Ce
- KI/KO Gene : Ceacam1
- Strain : Developing
- Description : Model Descripti
- Synonyms : Bgp, Cc1, Hv2,
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hFCGR2B/h4-1BB(2)
- Strain : Embryo cryopres
- KI/KO Gene : Fcgr2b
- Nomenclature : C57BL/6Smoc-Fcg
- Research Application : Immunotherapy
- Description : hFCGR2B(NM-HU-2
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hIFNGR1/hIFNGR2
- Strain : Embryo cryopres
- KI/KO Gene : IFNGR1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Ifn
- Description : hIFNGR1(NM-HU-1
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hIL12A/hIL12B/hIL12RB1/hIL12RB2
- Strain : Developing
- KI/KO Gene : Il12b
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il1
- Description : hIL12A(NM-HU-20
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