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Humanized Knockins
Shanghai Model Organisms Center, Inc.
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTSLP(M-NSG)
- Nomenclature : M-NSG-Tslptm(hT
- KI/KO Gene : Tslp
- Strain : Repository Live
- Description : Model Descripti
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pAtp4b-hCLDN18.2-Tg
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Tumor Targets
- Description : Model Descripti
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pAlb-hLPA-Tg
- Nomenclature : C57BL/6JSmoc-Tg
- KI/KO Gene : LPA
- Strain : Repository Live
- Target : Metabolic Targe
- Description : Model Descripti
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Rag2/IL2rg-KO/hKDR
- Nomenclature : C57BL/6JSmoc-Il
- KI/KO Gene : IL2RG
- Strain : Repository Live
- Description : Model Descripti
- Synonyms : gc, p64, (g)c
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R26-LSL-hIL4(M-NSG)
- Nomenclature : NOD-PrkdcscidIl
- KI/KO Gene : Gt(ROSA)26Sor
- Strain : Developing
- Description : Model Descripti
- Synonyms : R26, ROSA26, AV
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hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)
- Nomenclature : C57BL/6JSmoc-Si
- KI/KO Gene : Pdcd1
- Strain : Developing
- Target : Immune Checkpoi
- Description : Model Descripti
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hSIRPA(2)/hCD47
- Nomenclature : C57BL/6JSmoc-Si
- KI/KO Gene : SIRPA
- Research Application : Immunotherapy
- Strain : Repository Live
- Target : Immune Checkpoi
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