JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.
Loding Loading ....
Filter
Sort By

Humanized Knockins

Shanghai Model Organisms Center, Inc.

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

  • hPD-1/hPD-L1/hCTLA-4

    hPD-1/hPD-L1/hCTLA-4

    • Description : hCTLA4(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : CTLA4
    • Synonyms : Cd152; Ly-56;
  • hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)

    • Description : hSIRPA/hCD47(BA
    • Nomenclature : BALB/cAnSmoc-Pd
    • Strain : Developing
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hPD-L1(BALB/c)

    hPD-1/hPD-L1(BALB/c)

    • Description : hPD-1(BALB/c)(N
    • Nomenclature : BALB/cAnSmoc-Pd
    • Strain : Repository Live
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hTIGIT

    hTIGIT

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tig
    • Strain : Repository Live
    • KI/KO Gene : TIGIT
    • Synonyms : Vstm3
  • hTLR8/hPD-1

    hTLR8/hPD-1

    • Description : hTLR8(NM-HU-190
    • Nomenclature : C57BL/6Smoc-Tlr
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hTNFRSF1A

    hTNFRSF1A

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Embryo cryopres
    • KI/KO Gene : Sost
    • Synonyms : 5430411E23Rik
  • hTNFR2/hIL2RA

    hTNFR2/hIL2RA

    • Description : hTNFRSF1B(NM-HU
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Embryo cryopres
    • KI/KO Gene : IL2RA
    • Synonyms : CD25; Il2r; I
  • hTTR

    hTTR

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ttr
    • Strain : Sperm cryoprese
    • KI/KO Gene : Ttr
    • Synonyms : D17860; AA40876
  • hTREM2

    hTREM2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tre
    • Strain : Repository Live
    • KI/KO Gene : Trem2
    • Synonyms : TREM-2; Trem2a;
  • hVISTA

    hVISTA

    • Description : The exon 2-3 of
    • Nomenclature : C57BL/6Smoc-Vsi
    • Strain : Embryo cryopres
    • KI/KO Gene : Vsir
    • Synonyms : Dies1; PD-1H;
  • hPD-1/hIL1B

    hPD-1/hIL1B

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hSEMA4D

    hPD-1/hSEMA4D

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hPD-L1/hOX40

    hPD-1/hPD-L1/hOX40

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Embryo cryopres
    • KI/KO Gene : Tnfrsf4
    • Synonyms : Ox40; ACT35;
  • hPD-1/hVEGFR2

    hPD-1/hVEGFR2

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hTIM3

    hPD-1/hTIM3

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-L1/hCTLA-4

    hPD-L1/hCTLA-4

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Ctl
    • Strain : Embryo cryopres
    • KI/KO Gene : CTLA4
    • Synonyms : Cd152; Ly-56;
  • hPD-L1/hCD73(2)

    hPD-L1/hCD73(2)

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hPD-L1/hCD28

    hPD-L1/hCD28

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Repository Live
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hPD-L2(BALB/c)

    hPD-L2(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Pd
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1lg2
    • Synonyms : Btdc; B7-DC;
  • hPD-L1/hSIRPA(2)

    hPD-L1/hSIRPA(2)

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Sir
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hPVRL2

    hPVRL2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Nec
    • Strain : Repository Live
    • KI/KO Gene : Nectin2
    • Synonyms : MPH; Pvr; Pvs;
  • hPVRIG

    hPVRIG

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Pvr
    • Strain : Repository Live
    • KI/KO Gene : Pvrig
    • Synonyms : Gm36869
  • hPVR

    hPVR

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Pvr
    • Strain : Embryo cryopres
    • KI/KO Gene : Pvr
    • Synonyms : PVS, mE4, HVED,
  • hPTPRC

    hPTPRC

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ptp
    • Strain : Repository Live
    • KI/KO Gene : Ptprc
    • Synonyms : loc,B220,Cd45,L
  • hPSMA

    hPSMA

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Fol
    • Strain : Repository Live
    • KI/KO Gene : Folh1
    • Synonyms : GCP2; mopsm