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Humanized Knockins
Shanghai Model Organisms Center, Inc.
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hPD-1(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Pd
- Strain : Repository Live
- Synonyms : PD-1 Pdc1 Ly101
- Research Application : Immunotherapy
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hPD-1/hPD-L1
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hLAG3/hTIGIT
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : LAG3
- Synonyms : Ly66; CD223;
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hPD-1/hSTING
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Tme
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hPD-L1/hTIM3
- Description : hTIM3(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hPD-L1/hIDO1
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Ido
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-L1(2)/hCD28
- Description : hPD-L1(2)(NM-HU
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : B7h1,Pdl1,Pdcd1
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hPD-1/hTIGIT/hTIM3
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-L1/hCD40
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : CD40
- Synonyms : IGM; p50; Bp5
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hPD-L1/hCD27(2)
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Repository Live
- KI/KO Gene : CD27
- Synonyms : Cd27; S152; T
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hSIRPA(2)/hCD47/hCTLA-4
- Description : hCTLA4(NM-HU-00
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hSIRPA(2)/hCD47
- Description : This SIRPA and
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Repository Live
- KI/KO Gene : SIRPA
- Synonyms : Bit; P84; SIR
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h4-1BB(2)/hPD-1/hPD-L1
- Description : h4-1BB(2)(NM-HU
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hANGPTL3(4)
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Ang
- Strain : Repository Live
- KI/KO Gene : Angptl3
- Synonyms : hypl
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hCCR8/hPD-1
- Description : hCCR8(NM-HU-190
- Nomenclature : C57BL/6Smoc-Ccr
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hCCR8(2)/hCTLA-4
- Description : hCTLA4 (NM-HU-0
- Nomenclature : C57BL/6Smoc-Ccr
- Strain : Repository Live
- KI/KO Gene : CCR8
- Synonyms : Cmkbr8
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hCD28/hCD38(2)
- Description : hCD38(NM-HU-190
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : CD28
- Synonyms : Ly7, RP1, Ly78,
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hCD40/hCD40L
- Description : hCD40(NM-HU-000
- Nomenclature : C57BL/6Smoc-CD4
- Strain : Embryo cryopres
- KI/KO Gene : CD40
- Synonyms : IGM; p50; Bp5
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hCD40/hPD-1/hPD-L1
- Description : hPD-1/hPD-L1(NM
- Nomenclature : C57BL/6Smoc-Cd4
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hCTLA-4(2)
- Description : Extracellular d
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hTNFRSF10B
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Repository Live
- KI/KO Gene : Tnfrsf10b
- Synonyms : DR, KI, MK, TR,
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hTNFR2/hPD-1/hPD-L1
- Description : hTNFRSF1B(NM-HU
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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