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Humanized Knockins
Shanghai Model Organisms Center, Inc.
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTGFBR2(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Other Targets
- KI/KO Gene : Tgfbr2
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hTIGIT/hCCR8
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ti
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : CCR8
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hTIGIT(3)/hTNFRSF1B
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ti
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : TIGIT
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hTLR9/hOX40
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tl
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Tnfrsf4
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hTNFRSF12A
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Cytokine Recept
- KI/KO Gene : Tnfrsf12a
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hTNFRSF10B
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Embryo cryopres
- Target : Cytokine Recept
- KI/KO Gene : Tnfrsf10b
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hIL5/hIL5R
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : IL5
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hIL7(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Il7tm(hIL
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Il7
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hKDR(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Kd
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Kdr
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hMUC1-c.462insC
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Mu
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Muc1
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hIL2/hIL2RB/hIL2RG
- Description : hIL2RG(NM-HU-20
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : IL2
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hIL2/hIL2RA
- Description : hIL2(NM-HU-1900
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : IL2
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hIL2RA/hIL2RB/hIL2RG
- Description : hIL2RA(NM-HU-19
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : IL2RA
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hIL3/hCSF2/hSIRPA(2)/hCD47
- Description : hIL3(NM-HU-1900
- Nomenclature : C57BL/6Smoc-Il3
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : IL3
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hIL4/hIL4R
- Description : These mice are
- Nomenclature : C57BL/6Smoc-Il4
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : IL4
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hIL7(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Il7r
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hLILRB2-hLILRB3-Tg
- Description : These transgeni
- Nomenclature : C57BL/6Smoc-Tg(
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : LILRB2
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hOX40/Cd8a-IRES-Luc-2A-EGFP
- Description : hOX40(NM-HU-000
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Tnfrsf4
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