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Humanized Knockins
Shanghai Model Organisms Center, Inc.
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hIL7(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Il7tm(hIL
- Strain : Repository Live
- KI/KO Gene : Il7
- Synonyms : Il-7, hlb368, A
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hKDR(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Kd
- Strain : Developing
- KI/KO Gene : Kdr
- Synonyms : orv, Flk1, Ly73
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hMUC1-c.462insC
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Mu
- Strain : Repository Live
- KI/KO Gene : Muc1
- Synonyms : EMA, CD227, Muc
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hSIGLEC15(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Siglec15
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hSIRPA(2)/hCD47/hPD-1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
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hSIRPA(2)/hCD47/hCTLA-4
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : CTLA4
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hSTING(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-tm
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Tmem173
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hTIM3(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ha
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Havcr2
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hTIGIT(BALB/c,2)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ti
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Tigit
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