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Humanized Knockins
Shanghai Model Organisms Center, Inc.
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hCD27/hPD-L1(BALB/c)
- Nomenclature : BALB/cAnSmoc-Cd
- KI/KO Gene : CD27
- Strain : Developing
- Description : Model Descripti
- Synonyms : Cd27, S152, T
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hCD3E/hCD3D/hCD3G
- Nomenclature : C57BL/6JSmoc-Cd
- KI/KO Gene : CD3E
- Research Application : Immunotherapy
- Strain : Developing
- Description : Model Descripti
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hCD3EDG/hPSMA
- Nomenclature : C57BL/6JSmoc-Cd
- KI/KO Gene : CD3E
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- Description : Model Descripti
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hADORA2B(2)
- Nomenclature : C57BL/6JSmoc-Ad
- KI/KO Gene : Adora2b
- Strain : Developing
- Description : Model Descripti
- Synonyms : A2b, A2BR, A2BA
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hSIRPA(2)/hCD47/hPD-L1
- Nomenclature : C57BL/6JSmoc-Si
- KI/KO Gene : Cd274
- Research Application : Immunotherapy
- Strain : Repository Live
- Target : Immune Checkpoi
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hTHPO(M-NSG)
- Nomenclature : M-NSG-Thpotm(hT
- KI/KO Gene : Thpo
- Strain : Repository Live
- Description : Model Descripti
- Synonyms : Ml, Tpo, Mgdf,
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hTLR8/Lyz2-DTREGFP
- Nomenclature : C57BL/6JSmoc-Ly
- KI/KO Gene : TLR8
- Research Application : Tumor research
- Strain : Embryo cryopres
- Target : Immune Checkpoi
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hTNFRSF13C
- Nomenclature : C57BL/6JSmoc-Tn
- KI/KO Gene : Tnfrsf13c
- Strain : Developing
- Target : Cytokine Recept
- Description : Model Descripti
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hTNFRSF1B/hPD-1/hPD-L1
- Nomenclature : C57BL/6JSmoc-Tn
- KI/KO Gene : Pdcd1
- Strain : Developing
- Description : Model Descripti
- Synonyms : PD-1, Pdc1, Ly1
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hTNFRSF1B/hPD-1
- Nomenclature : C57BL/6JSmoc-Tn
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Description : Model Descripti
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