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Animal Model
Shanghai Model Organisms Center, Inc.
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Animal Model
Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.
1840 Result Found
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hIL1B(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- KI/KO Gene : IL1B
- Synonyms : Il-1b; IL-1bet
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hTLR9/hOX40
- Description : This TLR9 and O
- Nomenclature : C57BL/6Smoc-Tlr
- Strain : Embryo cryopres
- KI/KO Gene : Tnfrsf4
- Synonyms : Ox40; ACT35;
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hTLR8/Lyz2-DTREGFP
- Description : NM-KI-190041 wa
- Nomenclature : C57BL/6Smoc-Lyz
- Strain : Embryo cryopres
- KI/KO Gene : TLR8
- Synonyms : Ox40; ACT35;
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hTIGIT/hTNFR2
- Description : hTIGIT(3)(NM-HU
- Nomenclature : C57BL/6Smoc-Tig
- Strain : Repository Live
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hTNFR2/hPD-1
- Description : hTNFRSF1B(NM-HU
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hTNFa-Tg(DBA)
- Description : These transgeni
- Nomenclature : DBA-Tg(hTNFa)1S
- Strain : Developing
- KI/KO Gene : TNFRSF1B
- Synonyms : DIF,TNFA,TNFSF2
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hTSLP/hIL17RA
- Description : hTSLP(NM-HU-200
- Nomenclature : C57BL/6Smoc-Tsl
- Strain : Embryo cryopres
- KI/KO Gene : TSLP
- Synonyms : DIF,TNFA,TNFSF2
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Il12a-Luc-2A-EGFP
- Description : A Luciferase-2A
- Nomenclature : C57BL/6Smoc-Il1
- Strain : Embryo cryopres
- KI/KO Gene : Il12a
- Synonyms : IL-12p35 Il-12a
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Il18-Luc-2A-EGFP
- Description : A Luciferase-2A
- Nomenclature : C57BL/6Smoc-Il1
- Strain : Embryo cryopres
- KI/KO Gene : Il18
- Synonyms : Igif Il-18
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Il15-Luc-2A-EGFP
- Description : A Luciferase-2A
- Nomenclature : C57BL/6Smoc-Il1
- Strain : Embryo cryopres
- KI/KO Gene : Il15
- Synonyms : AI503618 IL-15
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Itgax-2A-tdTomato-2A-DTR
- Description : T2A-tdTomato-P2
- Nomenclature : C57BL/6Smoc-Itg
- Strain : Repository Live
- KI/KO Gene : Itgax
- Synonyms : Cr4; N418; Cd11
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Itgam-IRES-hCD89/hIGHA1
- Description : Itgam-IRES-hCD8
- Nomenclature : C57BL/6Smoc-Itg
- Strain : Repository Live
- KI/KO Gene : Itgam
- Synonyms : CR3; CR3A; MA
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Itgam-IRES-DTRGFP
- Description : A IRES-DTR-EGF
- Nomenclature : C57BL/6Smoc-Itg
- Strain : Repository Live
- KI/KO Gene : Itgam
- Synonyms : CR3; CR3A; MA
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MHC ClassII(I-A/I-E)-KO(NMG)
- Description : All sequences f
- Nomenclature : NOD-PrkdcscidIl
- Strain : Developing
- KI/KO Gene : H2-Ab1
- Synonyms : Abeta A beta H-
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Rag1-KO(Rag1-EGFP)
- Description : A loxP-EGFP-Pol
- Nomenclature : B6;129S-Rag1tm1
- Strain : Repository Live
- KI/KO Gene : Rag1
- Synonyms : Rag-1
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R26-pVillin1-hCYP3A4-IRES-tdTomato(FVB)
- Description : Intestinal expr
- Nomenclature : FVB-Gt(ROSA)26S
- Strain : Embryo cryopres
- KI/KO Gene : Gt(ROSA)26Sor
- Synonyms : R26,ROSA26,AV25
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R26-LSL-hIL15-Flag-IRES-EGFP
- Description : CAG-Loxp-Stop-L
- Nomenclature : C57BL/6Smoc-Gt(
- Strain : Sperm cryoprese
- KI/KO Gene : Gt(ROSA)26Sor
- Synonyms : R26,ROSA26,AV25
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hPD-1/hSIRPA(2)
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hTIGIT
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-L1/hLAG3
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Repository Live
- KI/KO Gene : LAG3
- Synonyms : Ly66; CD223;
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hPD-L1/hVEGFR2
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Repository Live
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hPD-L1/hTIM3
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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Hr-KO(NMG)
- Description : exon 2 of Hr ge
- Nomenclature : NOD-PrkdcscidIl
- Strain : Embryo cryopres
- KI/KO Gene : Hr
- Synonyms : N, AU, ba, hr,
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hPSGL-1(2)
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Sel
- Strain : Embryo cryopres
- KI/KO Gene : Selplg
- Synonyms : CD162; Psgl1; S
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hSIRPA(2)/hCD47/hPD-L1
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Repository Live
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)
- Description : hSIRPA(2)(NM-HU
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hSTING(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-tm
- Strain : Embryo cryopres
- KI/KO Gene : Tmem173
- Synonyms : ERIS; MPYS; M
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hTIGIT/hCCR8
- Description : hTIGIT(NM-HU-00
- Nomenclature : C57BL/6Smoc-Tig
- Strain : Embryo cryopres
- KI/KO Gene : CCR8
- Synonyms : Cmkbr8
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hIL21/hIL21R
- Description : hIL21(NM-HU-200
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL21
- Synonyms : IL-21
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hIL2/hIL2RA/hIL2RB/hIL2RG
- Description : hIL2/hIL2RA(NM-
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL2
- Synonyms : Il-2
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hIL2/hIL2RA(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- KI/KO Gene : IL2
- Synonyms : Il-2
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