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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hHBB

    hHBB

    • Strain : Repository Live
    • KI/KO Gene : Hbb-bt
    • Research Application : Thalassemia Res
    • Nomenclature : C57BL/6Smoc-Hbb
    • Description : The endogenous
  • hICOS(2)

    hICOS(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : Icos
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Ico
    • Description : The endogenous
  • hIGHG4

    hIGHG4

    • Strain : Repository Live
    • KI/KO Gene : Ighg1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Igh
    • Description : The endogenous
  • hIFNGR1/hIFNGR2

    hIFNGR1/hIFNGR2

    • Strain : Embryo cryopres
    • KI/KO Gene : IFNGR1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Ifn
    • Description : hIFNGR1(NM-HU-1
  • hIL13

    hIL13

    • Strain : Embryo cryopres
    • KI/KO Gene : IL13
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL12RB2

    hIL12RB2

    • Strain : Repository Live
    • KI/KO Gene : Ccr4
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL12A/hIL12B/hIL12RB1/hIL12RB2

    • Strain : Developing
    • KI/KO Gene : Il12b
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : hIL12A(NM-HU-20
  • hIL11

    hIL11

    • Strain : Embryo cryopres
    • KI/KO Gene : Il11
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL18

    hIL18

    • Strain : Sperm cryoprese
    • KI/KO Gene : Il18
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL17A

    hIL17A

    • Strain : Embryo cryopres
    • KI/KO Gene : IL17A
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL1B(BALB/c)

    hIL1B(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : IL1B
    • Research Application : Humanized Drug
    • Nomenclature : BALB/cAnSmoc-Il
    • Description : The endogenous
  • hIL1B

    hIL1B

    • Strain : Repository Live
    • KI/KO Gene : Il1b
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hTHPO

    hTHPO

    • Strain : Embryo cryopres
    • KI/KO Gene : Thpo
    • Research Application : Cytokine Humani
    • Nomenclature : C57BL/6Smoc-Thp
    • Description : The endogenous
  • hTLR9/hOX40

    hTLR9/hOX40

    • Strain : Embryo cryopres
    • KI/KO Gene : Tnfrsf4
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tlr
    • Description : This TLR9 and O
  • hTLR9

    hTLR9

    • Strain : Embryo cryopres
    • KI/KO Gene : Tlr9
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tlr
    • Description : This TLR9 human
  • hTLR8/Lyz2-DTREGFP

    hTLR8/Lyz2-DTREGFP

    • Strain : Embryo cryopres
    • KI/KO Gene : TLR8
    • Research Application : Tumor Research
    • Nomenclature : C57BL/6Smoc-Lyz
    • Description : NM-KI-190041 wa
  • hTLR4

    hTLR4

    • Strain : Embryo cryopres
    • KI/KO Gene : Tlr4
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Tlr
    • Description : The endogenous
  • hTIGIT/hTNFR2

    hTIGIT/hTNFR2

    • Strain : Repository Live
    • KI/KO Gene : CTLA4
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Tig
    • Description : hTIGIT(3)(NM-HU
  • hTNFR2/hPD-1

    hTNFR2/hPD-1

    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : hTNFRSF1B(NM-HU
  • hTNFR2

    hTNFR2

    • Strain : Repository Live
    • KI/KO Gene : TNFRSF1B
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : The endogenous
  • hTSLP/hIL17RA

    hTSLP/hIL17RA

    • Strain : Embryo cryopres
    • KI/KO Gene : TSLP
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tsl
    • Description : hTSLP(NM-HU-200
  • hTSLP

    hTSLP

    • Strain : Embryo cryopres
    • KI/KO Gene : TSLP
    • Research Application : Asthma Research
    • Nomenclature : C57BL/6Smoc-Tsl
    • Description : The endogenous
  • hTROP2

    hTROP2

    • Strain : Repository Live
    • KI/KO Gene : Tacstd2
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tac
    • Description : The endogenous
  • hTNFSF13B

    hTNFSF13B

    • Strain : Developing
    • KI/KO Gene : Tnfsf13b
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : The endogenous
  • hVEGFR2

    hVEGFR2

    • Strain : Embryo cryopres
    • KI/KO Gene : KDR
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Kdr
    • Description : The endogenous