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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

1840 Result Found
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  • Pten-Flox

    Pten-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pt
    • Exon : Exon s
    • KI/KO Gene : Pten
    • Synonyms : 2310035O07Rik A
  • R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Cancer
    • KI/KO Gene : Gt(ROSA)26Sor
  • R26-CAG-LSL-hIDH1*R132H-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Cancer Research
    • KI/KO Gene : Gt(ROSA)26Sor
  • R26-CAG-LSL-hFGFR3-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Cancer Research
    • KI/KO Gene : Gt(ROSA)26Sor
  • R26-CAG-LSL-hFGFR3*S249C-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Cancer Research
    • KI/KO Gene : Gt(ROSA)26Sor
  • R26-CAG-LSL-hTARDBP*A315T-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Amyotrophic Lat
    • KI/KO Gene : Gt(ROSA)26Sor
  • R26-CAG-LSL-hSOD1*G94A-IRES-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon s
    • Application : Amyotrophic Lat
    • Disease : Amyotrophic Lat
  • Slc6a3-KO

    Slc6a3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 4
    • Application : Dwarfism, Nervo
    • Disease : schizophrenia
  • Slc6a1-KO(3)

    Slc6a1-KO(3)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 7.
    • Application : Dwarfism, Nervo
    • Disease : schizophrenia
  • Slc34a1-KO

    Slc34a1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 3-6
    • Application : Research On Min
    • Disease : Hereditary Hypo
  • Srf-Flox

    Srf-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sr
    • Exon : Exon s
    • Application : Research On Min
    • Disease : Dilated Cardiom
  • Snrpn-KO

    Snrpn-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sn
    • Exon : Exon 6
    • Application : Related Researc
    • Disease : Prader-Willi Sy
  • Stat3-Flox(2)

    Stat3-Flox(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-St
    • Exon : Exon 18-20
    • Application : Study On Micror
    • Disease : inflammatory bo
  • Trp53-flox-R172H

    Trp53-flox-R172H

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Exon : Exon 18-20
    • Application : Spontaneous Tum
    • Disease : inflammatory bo
  • Tyro3-KO

    Tyro3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ty
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hFCRN(2)

    hFCRN(2)

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Fcg
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hFCGRT(NMG)

    hFCGRT(NMG)

    • Description : The background
    • Nomenclature : NOD-PrkdcscidIl
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hGDF15/hPD-1/hPD-L1

    hGDF15/hPD-1/hPD-L1

    • Description : hGDF15(NM-HU-21
    • Nomenclature : C57BL/6Smoc-Gdf
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hFGL1

    hFGL1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Fgl
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hICOS/hICOSL

    hICOS/hICOSL

    • Description : This ICOS and I
    • Nomenclature : C57BL/6Smoc-Ico
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hHLA-E

    hHLA-E

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Igs
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hHLA-A2

    hHLA-A2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-H2-
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hHLA-A11

    hHLA-A11

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-H2-
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hIL10

    hIL10

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hIFNGR2

    hIFNGR2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ifn
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hIL13/hOX40

    hIL13/hOX40

    • Description : hIL13(NM-HU-190
    • Nomenclature : C57BL/6Smoc-Il1
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hIL13(BALB/c)

    hIL13(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Il
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hIL12A

    hIL12A

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hIL11RA

    hIL11RA

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hIL17RB(2)

    hIL17RB(2)

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hIL1A(2)

    hIL1A(2)

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hIL1A

    hIL1A

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • Cd4-IRES-DTRGFP

    Cd4-IRES-DTRGFP

    • Description : A IRES-DTREGFP
    • Nomenclature : C57BL/6Smoc-Cd4
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • Cx3cr1-2A-EGFP

    Cx3cr1-2A-EGFP

    • Description : P2A-EGFP expres
    • Nomenclature : C57BL/6Smoc-Cx3
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • Crbn-I391V/Rag2-KO

    Crbn-I391V/Rag2-KO

    • Description : Crbn-I391V(NM-K
    • Nomenclature : C57BL/6Smoc-Crb
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • Clec4f-IRES-DTRGFP

    Clec4f-IRES-DTRGFP

    • Description : A IRES-DTRGFP
    • Nomenclature : C57BL/6Smoc-Cle
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • Cd8a-IRES-DTRGFP/Cd8a-IRES-Luc-2A-EGFP

    • Description : Cd8a-IRES-DTRGF
    • Nomenclature : C57BL/6Smoc-Cd8
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • H2/H2-D1-KO(NMG)

    H2/H2-D1-KO(NMG)

    • Description : Exon 1-6 of H2;
    • Nomenclature : NOD-PrkdcscidIl
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • H11-pT3(b)-hIL15-Flag

    H11-pT3(b)-hIL15-Flag

    • Description : pT3(b)-Kozak-hI
    • Nomenclature : C57BL/6Smoc-Igs
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA-4

    • Description : The Fcgr2b-Fcgr
    • Nomenclature : C57BL/6Smoc-Fcg
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hACE2-IRES-Luc-hAXL-Tg

    hACE2-IRES-Luc-hAXL-Tg

    • Description : These transgeni
    • Nomenclature : C57BL/6Smoc-Tg(
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • h4-1BBL

    h4-1BBL

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tnf
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hAppNL-G-F

    hAppNL-G-F

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-App
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hALB/hFCRN

    hALB/hFCRN

    • Description : hALB(NM-HU-2000
    • Nomenclature : C57BL/6Smoc-Alb
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hAHR

    hAHR

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ahr
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hCCR2

    hCCR2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ccr
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hCCL1

    hCCL1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ccl
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hCB1(2)

    hCB1(2)

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Cnr
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hCCR8/hCTLA-4

    hCCR8/hCTLA-4

    • Description : hCCR8(NM-HU-190
    • Nomenclature : C57BL/6Smoc-Ccr
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • hCCR8(BALB/c)

    hCCR8(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Cc
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise