Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Reactivity
Human, Mouse, Rat
uniprot enrty name
MP2K4_HUMAN
Note
This product is for research use only.
Clonality
polyclonal
Buffer
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Description
SEK1/MKK4 Antibody detects endogenous levels of total SEK1/MKK4. MKK4 dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38 but not ERK1 or -2. Mediates cellular responses to various cellular stresses and inflammatory cytokines. Phosphorylation by Akt inhibits MKK4 and suppresses stress-activated signal transduction.