Purified His-tagged Human PDGFR protein (Fragment)
Purification
Unpurified crude ascites.
Isotype
IgG Kappa
Tested Application
WB
Uniprotkb
P09619 (UniProt, ExPASy)
Availability
Shipped within 5-10 working days.
Target
PDGFR
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Reactivity
Mouse
uniprot enrty name
PGFRB_HUMAN
Note
This product is for research use only.
Clonality
monoclonal
Buffer
Ascites containing 0.09% sodium azide.
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Description
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq]. This antibody is supplied as crude ascites.