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Home / Primary Antibodies / Polyclonal Antibodies

WDR24 antibody

SKU : BHA10809462

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Mfr.No.	FNab09488
Alternative Names	C16orf21 ; DKFZp434F054 ; JFP7 ; WDrepeatdomain24 ; WDR24
Background	As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Nuleus
Clonality	polyclonal
Description	As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2 (PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).
Host	Rabbit
Immunogen	WD repeat domain 24
Isotype	IgG
Molecular Weight	102 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Cytoplasm, nuleus
Synonyms	C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24

Uniprot	Q96S15
Gene Id	84219
Research Area	Cell Division and Proliferation
Weight	102kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IF	1:10-1:100
IHC	1:20-1:200

Tested Application

WB: 1:500-1:5000; IP: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809462	FNab09488	100ug	$280		Add to Cart

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