Sudan Virus-like particles (VLP’s) expressing recombinant Sudan virus (SUDV) glycoprotein (GP), nucleoprotein (NP), and matrix protein (VP40). These VLP’s are produced in Sf9 insect cells through infection with a recombinant baculovirus. Relevance: Since these VLP’s mimic Sudan virus but do not contain genetic material, thus are not infectious and make an ideal candidate as a vaccine and also as a tool to enhance filovirus research.
Alternative Names
SUDV VLP
Expression
SF9 cells
Formulation
Supplied in PBS (supplemented with arginine and glutamic acid).
Target Details
Sudan virus-like particles
Pathogen Strain
Boniface
Target Pathogen
Sudan Virus
Virus Type
Filoviruses
Purification
Column chromatography
Storage
Store at 2-3 weeks at -20°C, -80°C long term
Notes
Please note: After thawing, VLP’s tend to sediment to the bottom of the tube and appear as aggregate pellet. VLP’s can be resuspended by gentle vortexing or by pipetting up and down, before use. Also, subaliquoting is recommended to avoid repeated freeze/thaw cycles