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Home / VECTOR &VIRUS / Lentivirus

ATF6 Reporter Lentivirus

SKU : BHV19400092

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Mfr.No.	LTV-0101, LTV-0101-1S, LTV-0101-2S, LTV-0101-3S, LTV-0101-4S, LTV-0101-5S, LTV-0101-6S, LTV-0101-15S, LTV-0101-16S
Description	ATF6 Reporter Lentivirus: High-quality, lentiviral transcription factor (TF) reporter system that provides a sensitive fluorescent or luminescent readout for human/mouse Activating transcription factor 6 (ATF6) transcriptional activity in mammalian cells. The ATF6 reporter is constructed with tandem repeats of consensus ATF6 DNA-binding elements to read out ATF6 transcriptional activity. ATF6 can be activated in ER stress response pathway to induce expression of ER chaperones and folding enzymes such as GRP78 and transcription factors such as XBP1 and other genes. The DNA binding sequence for ATF6 is related to but distinct from ATF1/CREB binding elements. The ATF6-specific element multiple-copy form has been shown activated by active form ATF6 and strongly induced by the ER stress stimuli such as tunicamycin. The ATF6 reporter lentivirus is purified by PEG precipitation and sucrose gradient centrifugation and is ideal for studying ATF6 transcriptional activity in difficult-to-transfect cells including primary and/or thawed cells.
Serotype	VSV-G
Reporter	Firefly Luc, RFP, BFP2, GFP
Response Element	ATF6 response element
Selection	Blasticidin, Puromycin
Signaling pathway	ATF6 Signaling Pathway
Species	Human/mouse
Applications Range	Monitor ATF6 transcriptional activity in mammalian cells, screen for activators or inhibitors of ATF6 transcriptional activity. The fluorescent reporter enables convenient readout using flow cytometry, fluorescence microscopy, etc.
Virus Type	TF Reporter Lentivirus

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Combination SKU	Supplier No.	Amount (TU)	Selection	Reporter	Your price	Quantity
BHV19400092-1	LTV-0101-1S	5x10^6	Puromycin	GFP	$595		Add to Cart
BHV19400092-2	LTV-0101-2S	5x10^6	Blasticidin	RFP	$595		Add to Cart
BHV19400092-3	LTV-0101-3S	2x10^6	Puromycin	Firefly Luc	$595		Add to Cart
BHV19400092-4	LTV-0101-4S	2x10^6	Blasticidin	Firefly Luc	$595		Add to Cart
BHV19400092-5	LTV-0101-5S	5x10^6	Blasticidin	GFP	$595		Add to Cart
BHV19400092-6	LTV-0101-6S	5x10^6	Puromycin	RFP	$595		Add to Cart
BHV19400092-7	LTV-0101-15S	5x10^6	Puromycin	BFP2	$595		Add to Cart
BHV19400092-8	LTV-0101-16S	5x10^6	Blasticidin	BFP2	$595		Add to Cart

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