R26-CAG-2xKRAB-dCas9-IRES-EGFP

Mfr.No.	NM-KI-18007
Description	Model Description: These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted. Official Symbol: Gt(ROSA)26Sor NCBI ID link: 14910 MGI ID link: 104735 Ensembl ID link: ENSMUSG00000086429 Pubmed link: Gt(ROSA)26Sor
Nomenclature	C57BL/6JSmoc-Gt(ROSA)26Sor^{em1(CAG-Loxp-}^2xKRAB^{-dCas9-IRES-EGFP)Smoc}
Strain	Embryo cryopreservation
KI/KO Gene	Gt(ROSA)26Sor
Synonyms	R26, ROSA26, AV258896, Gtrgeo26, Gtrosa26, Thumpd3as1

Applications Range	CRISPRi,gene regulation tool
Research Application	CRISPR/Cas knockins

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