Ptf1a-CreERT2

Mfr.No.	NM-KI-200118
Description	Model Description: A CreERT2-WPRE-pA expression cassette was knocked into the Ptf1a gene start codon site. Official Symbol: Ptf1a NCBI ID link: 19213 MGI ID link: 1328312 Ensembl ID link: ENSMUSG00000026735 Pubmed link: Ptf1a Human Ortholog: PTF1A
Nomenclature	C57BL/6JSmoc-Ptf1a^{em1(CreERT2-WPRE-pA)Smoc}
Strain	Repository Live
KI/KO Gene	Ptf1a
Synonyms	PTF1p48, bHLHa29, PTF1-p48

Applications Range	These mice express cre recombinase from the Ptf1a locus. By mating the reporter mice with CreERT2-expressing mice, reporter gene expression can be detected in the pancreatic acinar cells of the Ptf1aCreERT2/+ ; Rosa26tdTomato/+ mouse. And the mice are useful for generating conditional mutations in pancreatic acinar cells. This strain may be useful for in the research of pancreatic cancer.
Research Application	Cre/Dre-Driver

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