Prom1-CreERT2

Mfr.No.	NM-KI-200169
Description	Model Description: A CreERT2-PolyA expression cassette was knocked into the Prom1 gene start codon site. Prom1 encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. When these Prom1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Prom1 expressing cells. Official Symbol: Prom1 NCBI ID link: 19126 MGI ID link: 1100886 Ensembl ID link: ENSMUSG00000029086 Pubmed link: Prom1 Human Ortholog: PROM1
Nomenclature	C57BL/6JSmoc-Prom1^{em1(CreERT2-PolyA)Smoc}
Strain	Sperm cryopreservation
KI/KO Gene	Prom1
Synonyms	Prom, AC133, CD133, Prom-1, Proml1, 4932416E19Rik

Applications Range	Cre recombinase tool; Stem cell
Research Application	Cre/Dre-Driver

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