Penk-IRES-Cre

Mfr.No.	NM-KI-200088
Description	Model Description: A IRES2-iCre expression cassette was knocked into the Penk gene stop codon site. Official Symbol: Penk NCBI ID link: 18619 MGI ID link: 104629 Ensembl ID link: ENSMUSG00000045573 Pubmed link: Penk Human Ortholog: PENK
Nomenclature	C57BL/6JSmoc-Penk^{em1(IRES2-iCre)Smoc}
Strain	Embryo cryopreservation
KI/KO Gene	Penk
Synonyms	ENK, PPA, Penk1, AI326464

Applications Range	Penk gene encodes prodynorphin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The gene product is involved in regulating synaptic plasticity, a crucial neurochemical mechanism underlying learning and memory.
Research Application	Cre/Dre-Driver

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