Oprk1-2A-Cre

Mfr.No.	NM-KI-200299
Description	Model Description: 2A-Cre expression cassette was knocked into the Oprk1 gene stop codon site. Oprk1 (opioid receptor, kappa 1) encodes opioid receptor which was expressed in multiple brain regions. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Official Symbol: Oprk1 NCBI ID link: 18387 MGI ID link: 97439 Ensembl ID link: ENSMUSG00000025905 Pubmed link: Oprk1 Human Ortholog: OPRK1
Nomenclature	C57BL/6JSmoc-Oprk1^{em1(2A-Cre)Smoc}
Strain	Sperm cryopreservation
KI/KO Gene	Oprk1
Synonyms	KOR, R21, KOR-1, MSL-1, Oprk2, K-OR-1

Applications Range	Cre recombinase tool; Neuroscience
Research Application	Cre/Dre-Driver

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