Ascl1-CreERT2

Mfr.No.	NM-KI-200207
Description	Model Description: A CreERT2-Wpre-pA expression cassette was knocked into the Ascl1 gene start codon site. Official Symbol: Ascl1 NCBI ID link: 17172 MGI ID link: 96919 Ensembl ID link: ENSMUSG00000020052 Pubmed link: Ascl1 Human Ortholog: ASCL1
Nomenclature	C57BL/6JSmoc-Ascl1^{em1(CreERT2-Wpre-pA)Smoc}
Strain	Embryo cryopreservation
KI/KO Gene	Ascl1
Synonyms	ASH1, Mash1, bHLHa46, AI225900

Applications Range	When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre after tamoxifen treatment. These mice may be useful in studying the role of Ascl1 positive neural progenitor cells in the neuronal turnover and neuronal replacement.
Research Application	Cre/Dre-Driver

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