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Home / Primary Antibodies

SREBP2 Antibody / SREBF2 (V8100SAF)

SKU : BHA17127220

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NSJ Bioreagents

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Mfr.No.	V8100SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1). When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	A recombinant full-length human protein was used as the immunogen for this SREBP2 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the antibody should be determined by the researcher.

Uniprot	Q12772

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the SREBP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	ELISA
Description	ELISA (order BSA-free format for coating)

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/srebp2-antibody-srebp2-1579-v8100" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17127220	V8100SAF-100UG	100 ug	$499		Add to Cart

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