ZNL 02-096

Mfr.No.	T41163
Description	ZNL 02-096 (Pomalidomide-C3-adavosertib) is a rapid and selective degrader of Wee1 (IC50=3.58 nM).ZNL 02-096 selectively degrades Wee1 at submolar concentrations without damaging PLK1, a secondary target of AZD 1775.ZNL 02-096 induces degradation of Wee1 and accumulation of DNA damage in MOLT-4 cells in vitro, In vitro in MOLT-4 cells, ZNL 02-096 induced Wee1 degradation, accumulation of DNA damage, cell cycle arrest in G2/M phase and apoptosis.ZNL 02-096 showed anti-proliferative effects in 300 cancer cell lines.
Alternative Names	Pomalidomide-C3-adavosertib
Molecular Formula	C42H45N11O6
Signaling Pathways	Apoptosis, Cell Cycle/Checkpoint
Smiles	C(C=C)N1N(C=2C(C1=O)=CN=C(NC3=CC=C(C=C3)N4CCN(CCCNC5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5)CC4)N2)C=8N=C(C(C)(C)O)C=CC8
Cas Number	2414418-49-6
Molecular Weight	799.88
Target	Wee1, Apoptosis

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SKU	Supplier No.	Size	Your price
BHB20428893	T41163	1 mg	$263	Add to Cart
BHB20428893	T41163	2 mg	$392	Add to Cart
BHB20428893	T41163	5 mg	$668	Add to Cart
BHB20428893	T41163	10 mg	$892	Add to Cart
BHB20428893	T41163	25 mg	$1350	Add to Cart
BHB20428893	T41163	50 mg	$1820	Add to Cart
BHB20428893	T41163	100 mg	$2450	Add to Cart