Zafirlukast

Mfr.No.	SIH-361
Alternative Names	Cyclopentyl [3-(2-methoxy-4-{[(2-methylphenyl)sulfonyl]carbamoyl}benzyl)-1-methyl-1H-indol-5-yl]carbamate; ICI-204219
Appearance	White to Pink Solid
Function	Hsp70 Inhibitor
Inchi	InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32,36)(H,33,35)
Inchikey	YEEZWCHGZNKEEK-UHFFFAOYSA-N
Mode Of Action	Inhibitor
Molecular Formula	C31H33N3O6S
Pubchem Cid	5717148
Research Area	Cancer ; Heat Shock
Safety Phrases	Classification: Caution- Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes
Smiles	CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(C=C2)CC3=CN(C4=C3C=C(C=C4)NC(=O)OC5CCCC5)C)OC
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	107753-78-6
Molecular Weight	575.7
Scientific Background	HSP70 inhibitor ( IC50=37 µM). Leukotriene antagonist. Clinically useful antiasthmatic agent. Cell permeable. Looking for more information on HSP70? Visit our new HSP70 Scientific Resource Guide at http://www.HSP70.com.
Solubility	Soluble in 25 mg/ml DMSO
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Miyata Y., et al. (2010) J. Biomol. 15: 1211.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900149-1	SIH-361-10MG	10 mg	$87		Add to Cart