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THZ-P1-2

SKU : BHB20427896

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Description
Review(s)

Mfr.No.	T39459
Description	THZ-P1-2 is a novel, specific inhibitor of PI5P4K that effectively targets PI5P4Kalpha. With an IC 50 of 190 nM, THZ-P1-2 selectively inhibits PI5P4Kalpha by forming covalent bonds with cysteine residues located on a disordered loop present in PI5P4Kalpha/beta/gamma. This mechanism not only disrupts autophagy but also elevates TFEB signaling. Moreover, THZ-P1-2 exhibits potent anticancer effects in leukemia cell lines, making it a promising candidate for therapeutic applications.
Molecular Formula	C31H29N7O2
Signaling Pathways	Others
Smiles	CN(C)CC=CC(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2cc(ncn2)-c2c(nH)c3ccccc23)c1
Cas Number	2058075-45-7
Molecular Weight	531.62
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20427896	T39459	5 mg	$427		Add to Cart

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THZ-P1-2

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