TD52 dihydrochloride

Mfr.No.	T35528L
Description	TD52 dihydrochloride (TD52 2HCl), a derivative of Erlotinib, is a potent and orally active inhibitor of protein phosphatase 2A (CIP2A). It exhibits strong anti-cancer properties by regulating the CIP2A/PP2A/p-Akt signaling pathway, resulting in the induction of apoptosis in triple-negative breast cancer (TNBC) cells. Mechanistically, TD52 dihydrochloride disrupts the binding of Elk1 to the CIP2A promoter, effectively reducing CIP2A levels. Notably, TD52 dihydrochloride demonstrates powerful anti-cancer activity while displaying less inhibition of p-EGFR.
Alternative Names	TD52 dihydrochloride(1798328-24-1 Free base)
Molecular Formula	C24H18Cl2N4
Signaling Pathways	Others
Smiles	CCC1=CC=CC(NC2=NC3=C(N=C2NC4=CC(CC)=CC=C4)C=CC=C3)=C1.Cl.Cl
Molecular Weight	433.33
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20424949	T35528L	1 mL	$45	Add to Cart
BHB20424949	T35528L	5 mg	$39	Add to Cart
BHB20424949	T35528L	10 mg	$76	Add to Cart
BHB20424949	T35528L	25 mg	$172	Add to Cart
BHB20424949	T35528L	50 mg	$271	Add to Cart
BHB20424949	T35528L	100 mg	$397	Add to Cart