Sodium Valproate

Mfr.No.	SIH-357
Alternative Names	2-Propylpentanoic acid Na
Appearance	White Solid
Function	HDAC inhibitor
Inchi	InChI=1S/C8H16O2.Na/c1-3-5-7(6-4-2)8(9)10;/h7H,3-6H2,1-2H3,(H,9,10);/q;+1/p-1
Inchikey	AEQFSUDEHCCHBT-UHFFFAOYSA-M
Mode Of Action	Inhibitor
Molecular Formula	C8H15NaO2
Pubchem Cid	16760703
Research Area	Cell Signaling ; Epigenetics and Nuclear Signaling ; Cancer
Safety Phrases	Classification: Caution- Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes
Smiles	CCCC(CCC)C(=O)[O-].[Na+]
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	1069-66-5
Molecular Weight	166.2
Scientific Background	Histone deacetylase inhibitor (IC50=400 µM). Demonstrates neuroprotective, anticancer and anti-inflammatory activity. Inhibits Aβ production and neuritic plaque formation in Alzheimer's mouse models. Clinically useful anticonvulsant.
Solubility	Soluble in 50 mg/ml Water
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Phiel C.J., et al. (2001) J. Biol. Chem. 276: 36734. 2. Kim H.J., et al. (2007) J. Pharmacol. Exp. Ther. 321: 892. 3. Qing H., et al. (2008) J. Exp. Med. 205: 2781.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900145-1	SIH-357-5G	5 g	$31		Add to Cart