Rasagiline mesylate

Mfr.No.	SIH-577
Alternative Names	(1R)-2,3-Dihydro-N-2-propynyl-1H-inden-1-amine, methanesulfonate; TVP-1012; Azilect
Appearance	White crystalline powder
Function	MAO inhibitor
Inchi	InChI=1S/C12H13N.CH4O3S/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12;1-5(2,3)4/h1,3-6,12-13H,7-9H2;1H3,(H,2,3,4)/t12-;/m1./s1
Inchikey	JDBJJCWRXSVHOQ-UTONKHPSSA-N
Mode Of Action	Inhibitor
Molecular Formula	C12H13N • CH3SO3H
Pubchem Cid	3052775
Research Area	Neuroscience ; Neurodegeneration ; Parkinson's Disease ; Synuclein
Safety Phrases	GHS Classification: GHS07 Acute Toxicity (Category 4), Skin Irritant (Category 2), Eye Irritant (Category 2), Specific Target Organ Toxicity (Category 3); Hazard Statement: H302 Harmful if Swallowed
Smiles	C#CCN[C@@H]2CCC1=CC=CC=C12.CS(=O)(O)=O
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	161735-79-1
Molecular Weight	267.3
Scientific Background	Rasagiline mesylate is an effective therapeutic in the early stages of Parkinon's Disease as it prevents the breakdown of dopamine by irreversibly binding to MAO-B. It has neuroprotective effects and increases the survival of dopaminergic neurons (1). ; It prevents alpha synculein induced dopaminergic meuronal death and rescues TrkB neurotrophic signaling (2).
Solubility	May be dissolved in DMSO (50 mg/ml); or water (50 mg/ml); Ethanol (30 mg/ml)
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Stocchi F., Fossati C1, Torti M. (2015) Expert Opin Pharamcorther. 16(14): 2231-2241. 2. Chau KY., Cooper JM., Schapire AHV. (2010) Neurochem Int. 57(5): 525-529.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900355-1	SIH-577-50MG	50 mg	$62		Add to Cart
BHB11900355-2	SIH-577-250MG	250 mg	$246		Add to Cart