PRGL493

Mfr.No.	T35666
Description	PRGL493 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4).1It inhibits formation of arachidonoyl-CoA (AA-CoA) from arachidonic acid in, as well as the proliferation and migration of, PC3 and MDA-MB-231 cancer cells when used at a concentration of 50 uM. PRGL493 (5 uM) reduces production of progesterone induced by 8-Br-cyclic AMP (8-Br-cAMP) in MA-10 Leydig tumor cells. It inhibits tumor growth in a PC3 mouse xenograft model when administered at a dose of 0.25 mg/kg.
Molecular Formula	C25H21N7O2
Signaling Pathways	Others
Smiles	N(C(C)=O)C1=NC(N2C=3C(NC2=N1)=CC=CC3)C=4C(=NN(C4)C5=CC=CC=C5)C=6OC(C)=CC6
Cas Number	2479378-45-3
Molecular Weight	451.48
Target	Others

Have you used this product?

SKU	Supplier No.	Size	Your price
BHB20425075	T35666	1 mg	$59	Add to Cart
BHB20425075	T35666	5 mg	$147	Add to Cart
BHB20425075	T35666	10 mg	$239	Add to Cart
BHB20425075	T35666	25 mg	$392	Add to Cart
BHB20425075	T35666	50 mg	$588	Add to Cart
BHB20425075	T35666	100 mg	$838	Add to Cart