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PLX5622 hemifumarate

SKU : BHB20404351

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Description
Review(s)

Mfr.No.	T12505
Description	PLX5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor with an IC 50 of 0.016 uM and Ki of 5.9 nM. PLX5622 hemifumarate allows for extended and specific microglial elimination, preceding and during pathology development. In vivo, PLX5622 hemifumarate demonstrates desirable PK properties in varies animals (1) (2).
Molecular Formula	C25H23F2N5O5
Signaling Pathways	Tyrosine Kinase/Adaptors
Smiles	COC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2.O=C(O)/C=C/C(O)=O.(1/2)
Molecular Weight	453.45
Target	c-Fms

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SKU	Supplier No.	Size	Your price	Quantity
BHB20404351	T12505	200 mg	$1168		Add to Cart

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PLX5622 hemifumarate

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