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PI3K?/HDAC6-IN-1

SKU : BHB20444078

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Description
Review(s)

Mfr.No.	T79710
Description	PI3Kalpha/HDAC6-IN-1 (compound 21j) is a dual inhibitor of PI3Kalpha and HDAC6, exhibiting IC50 values of 2.9 nM and 26 nM, respectively. It effectively hinders AKT(Ser473) phosphorylation and promotes the build-up of acetylated alpha-tubulin, while not influencing acetylated histones H3 and H4. The compound demonstrates potent anti-cancer efficacy by inhibiting the L-363 cell line with an IC50 of 0.17 uM (1).
Molecular Formula	C27H30F3N7O6S2
Signaling Pathways	Chromatin/Epigenetic, DNA Damage/DNA Repair
Molecular Weight	669.7
Target	HDAC

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SKU	Supplier No.	Size	Your price	Quantity
BHB20444078	T79710	5 mg	-		Add to Quote
BHB20444078	T79710	50 mg	-		Add to Quote

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PI3K?/HDAC6-IN-1

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