NSC59984

Mfr.No.	SIH-542
Alternative Names	NSC59984, NSC-59984, NSC59984, MLS000737358, SMR000528276, (E)-1-(4-methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one, 803647-40-7, AC1NS9AU, CID 5356520, MLS000737358, 1-Methyl-4-[3-(5-nitro-2-furanyl)-1-oxo-2-propenyl]-piperazine, 1-(4-Methyl-1-piperazinyl)-3-(5-nitro-2-furanyl)-2-propen-1-one
Appearance	Yellow to brown powder
Function	p53-MDM2 inhibitor
Inchi	1S/C12H15N3O4/c1-13-6-8-14(9-7-13)11(16)4-2-10-3-5-12(19-10)15(17)18/h2-5H,6-9H2,1H3/b4-2+
Inchikey	QKTRIGNWBRHBFV-DUXPYHPUSA-N
Mode Of Action	Inhibitor
Molecular Formula	C12H15N3O4
Pubchem Cid	5356520
Research Area	Cancer ; Cancer Growth Inhibitors ; p53/mdm2 Inhibitors
Safety Phrases	Classification: D2B Toxic Material Causing Other Toxic Effects - Moderate skin irritant, Moderate respiratory irritant, Moderate eye irritant Hazard statement(s): H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary statement(s): P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of water. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant.
Smiles	CN1CCN(CC1)C(=O)C=CC2=CC=C(O2)[N+](=O)[O-]
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	803647-40-7
Molecular Weight	265.3
Scientific Background	NSC59984 acts on the mutant p53/MDM2 pathway in tumor cells to restore normal function. It is not cytotoxic in healthy cells.
Solubility	Soluble in DMSO (5 mg/ml)
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Shipping Temperature	Shipped Ambient
Gross Weight (kg)	0.25
Net Weight (g)	0.025
Purity	>98%
Storage Temperature	-20ºC
Stock Product	Y

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900321-1	SIH-542-5MG	5 mg	$73		Add to Cart
BHB11900321-2	SIH-542-25MG	25 mg	$281		Add to Cart

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