Nolatrexed dihydrochloride

Mfr.No.	T2627
Description	Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity.
Alternative Names	Thymitaq
Molecular Formula	C14H14Cl2N4OS
Signaling Pathways	DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Smiles	Cl.Cl.Cc1ccc2nc(N)(nH)c(=O)c2c1Sc1ccncc1
Cas Number	152946-68-4
Molecular Weight	357.26
Target	DNA/RNA Synthesis

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SKU	Supplier No.	Size	Your price
BHB20416126	T2627	1 mL	$39	Add to Cart
BHB20416126	T2627	5 mg	$44	Add to Cart
BHB20416126	T2627	10 mg	$73	Add to Cart
BHB20416126	T2627	25 mg	$147	Add to Cart
BHB20416126	T2627	50 mg	$229	Add to Cart